STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZOSMA_72G00030Mitochondrial intermediate peptidase. (705 aa)    
Predicted Functional Partners:
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
      
 0.467
A0A0K9PY16
Xaa-Pro dipeptidase.
   
 
 0.466
ZOSMA_52G01000
Ferroxidase.
   
 
 0.441
ZOSMA_76G00630
Peptidase M48 family protein.
  
  
 0.437
ZOSMA_68G00860
Presequence protease 1, chloroplastic/mitochondrial.
    
 
 0.434
ZOSMA_66G00240
Putative Mitochondrial intermediate peptidase.
  
   
0.431
ZOSMA_52G01110
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial.
   
  
 0.427
ZOSMA_56G01480
Putative Aspartic proteinase; Belongs to the peptidase A1 family.
   
  
 0.421
ZOSMA_8G01920
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
      
 0.420
ZOSMA_1G00570
Proteasome endopeptidase complex.
      
 0.410
Your Current Organism:
Zostera marina
NCBI taxonomy Id: 29655
Other names: Z. marina, Zostera marina L.
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