ZOSMA_52G00240 protein (Zostera marina) - STRING interaction network

Nodes:

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query proteins and first shell of interactors

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second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

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Score

ZOSMA_52G00240

Uncharacterized protein. (692 aa)

Predicted Functional Partners:

ZOSMA_40G00230

0.514

ZOSMA_19G00220

0.514

ZOSMA_24G01450

0.489

ZOSMA_82G00750

0.475

ZOSMA_74G00080

0.470

ZOSMA_96G00480

0.455

ZOSMA_17G00800

0.455

ZOSMA_79G00380

0.449

ZOSMA_54G01200

0.449

ZOSMA_91G00020

0.410

Your Current Organism:

Zostera marina

NCBI taxonomy Id: 29655
Other names: Z. marina, Zostera marina L.

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ZOSMA_17G00800	ZOSMA_24G01450	A0A0K9PTF7	A0A0K9PGF4	Lys-63-specific deubiquitinase BRCC36.	BRISC and BRCA1-A complex member 1.	0.985
ZOSMA_17G00800	ZOSMA_52G00240	A0A0K9PTF7	A0A0K9NXF8	Lys-63-specific deubiquitinase BRCC36.	Uncharacterized protein.	0.455
ZOSMA_17G00800	ZOSMA_96G00480	A0A0K9PTF7	A0A0K9NJW3	Lys-63-specific deubiquitinase BRCC36.	26S proteasome regulatory subunit.	0.422
ZOSMA_19G00220	ZOSMA_52G00240	A0A0K9PQB7	A0A0K9NXF8	60S ribosomal protein L21, putative, expressed.	Uncharacterized protein.	0.514
ZOSMA_19G00220	ZOSMA_82G00750	A0A0K9PQB7	A0A0K9NM13	60S ribosomal protein L21, putative, expressed.	60S ribosomal protein L39.	0.998
ZOSMA_19G00220	ZOSMA_91G00020	A0A0K9PQB7	A0A0K9NJ01	60S ribosomal protein L21, putative, expressed.	Uncharacterized protein.	0.978
ZOSMA_24G01450	ZOSMA_17G00800	A0A0K9PGF4	A0A0K9PTF7	BRISC and BRCA1-A complex member 1.	Lys-63-specific deubiquitinase BRCC36.	0.985
ZOSMA_24G01450	ZOSMA_52G00240	A0A0K9PGF4	A0A0K9NXF8	BRISC and BRCA1-A complex member 1.	Uncharacterized protein.	0.489
ZOSMA_24G01450	ZOSMA_96G00480	A0A0K9PGF4	A0A0K9NJW3	BRISC and BRCA1-A complex member 1.	26S proteasome regulatory subunit.	0.977
ZOSMA_40G00230	ZOSMA_52G00240	A0A0K9P332	A0A0K9NXF8	60S ribosomal protein L21, putative, expressed.	Uncharacterized protein.	0.514
ZOSMA_40G00230	ZOSMA_82G00750	A0A0K9P332	A0A0K9NM13	60S ribosomal protein L21, putative, expressed.	60S ribosomal protein L39.	0.998
ZOSMA_40G00230	ZOSMA_91G00020	A0A0K9P332	A0A0K9NJ01	60S ribosomal protein L21, putative, expressed.	Uncharacterized protein.	0.978
ZOSMA_52G00240	ZOSMA_17G00800	A0A0K9NXF8	A0A0K9PTF7	Uncharacterized protein.	Lys-63-specific deubiquitinase BRCC36.	0.455
ZOSMA_52G00240	ZOSMA_19G00220	A0A0K9NXF8	A0A0K9PQB7	Uncharacterized protein.	60S ribosomal protein L21, putative, expressed.	0.514
ZOSMA_52G00240	ZOSMA_24G01450	A0A0K9NXF8	A0A0K9PGF4	Uncharacterized protein.	BRISC and BRCA1-A complex member 1.	0.489
ZOSMA_52G00240	ZOSMA_40G00230	A0A0K9NXF8	A0A0K9P332	Uncharacterized protein.	60S ribosomal protein L21, putative, expressed.	0.514
ZOSMA_52G00240	ZOSMA_54G01200	A0A0K9NXF8	A0A0K9NWQ3	Uncharacterized protein.	LYR motif-containing protein 4B; Belongs to the complex I LYR family.	0.449
ZOSMA_52G00240	ZOSMA_74G00080	A0A0K9NXF8	A0A0K9NRH8	Uncharacterized protein.	Mitochondrial import receptor subunit TOM40.	0.470
ZOSMA_52G00240	ZOSMA_79G00380	A0A0K9NXF8	A0A0K9NN73	Uncharacterized protein.	CYTB_NTER domain-containing protein.	0.449
ZOSMA_52G00240	ZOSMA_82G00750	A0A0K9NXF8	A0A0K9NM13	Uncharacterized protein.	60S ribosomal protein L39.	0.475

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Network Stats

number of nodes:

11

number of edges:

40

average node degree:

7.27

avg. local clustering coefficient:

0.923

expected number of edges:

14

PPI enrichment p-value:

6.66e-09

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016558

Protein import into peroxisome matrix

9 of 13

2.88

10.37

6.14e-21

GO:0016560

Protein import into peroxisome matrix, docking

5 of 6

2.96

5.77

1.86e-11

GO:0006886

Intracellular protein transport

10 of 275

1.6

3.49

1.39e-13

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005052

Peroxisome matrix targeting signal-1 binding

2 of 2

3.04

1.2

0.0069

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005778

Peroxisomal membrane

8 of 33

2.42

7.05

1.09e-15

GO:0005777

Peroxisome

9 of 87

2.05

5.81

1.22e-15

GO:1990429

Peroxisomal importomer complex

4 of 4

3.04

4.57

4.03e-09

GO:0016020

Membrane

9 of 2199

0.65

0.53

0.00075

GO:0005829

Cytosol

5 of 821

0.82

0.49

0.0288

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:9523

Protein import into peroxisome matrix, and Pex19 protein

9 of 15

2.82

10.18

8.65e-21

CL:9540

Peroxisomal importomer complex, and Pex19 protein

3 of 5

2.82

2.74

9.38e-06

CL:9525

Protein import into peroxisome matrix, and Bile acid metabolic process

3 of 6

2.74

2.67

1.21e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04146

Peroxisome

9 of 92

2.03

5.73

1.11e-15

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-9033241

Peroxisomal protein import

9 of 139

1.85

4.44

2.49e-13

MAP-9609507

Protein localization

9 of 216

1.66

3.47

5.83e-12

MAP-9603798

Class I peroxisomal membrane protein import

4 of 22

2.3

2.94

1.73e-06

MAP-9664873

Pexophagy

2 of 9

2.39

1.09

0.0097

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005778

Peroxisomal membrane

7 of 27

2.45

6.16

2.28e-13

GOCC:0005777

Peroxisome

8 of 94

1.97

4.71

1.01e-12

GOCC:0016020

Membrane

8 of 1387

0.8

0.68

0.00051

GOCC:0005737

Cytoplasm

9 of 2852

0.54

0.39

0.0096

GOCC:0005622

Intracellular

11 of 5889

0.31

0.24

0.0404

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF04757

Pex2 / Pex12 amino terminal region

2 of 2

3.04

1.28

0.0050

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR025655

Peroxisomal membrane protein 14

2 of 2

3.04

1.03

0.0139

IPR024111

PEX5/PEX5L

2 of 2

3.04

1.03

0.0139

IPR006845

Pex, N-terminal

2 of 2

3.04

1.03

0.0139

IPR006785

Peroxisome membrane anchor protein Pex14p, N-terminal

2 of 2

3.04

1.03

0.0139

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