ZOSMA_26G01170 protein (Zostera marina) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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ZOSMA_26G01170

AT-hook motif nuclear-localized protein; Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs). (319 aa)

Predicted Functional Partners:

ZOSMA_64G00560

0.511

ZOSMA_18G00430

0.511

A0A0K9Q2R8

0.511

ZOSMA_64G00580

0.420

Your Current Organism:

Zostera marina

NCBI taxonomy Id: 29655
Other names: Z. marina, Zostera marina L.

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0K9Q2R8	ZOSMA_18G00430	A0A0K9Q2R8	A0A0K9PRV2	BHLH domain-containing protein.	BHLH domain-containing protein.	0.540
A0A0K9Q2R8	ZOSMA_26G01170	A0A0K9Q2R8	A0A0K9PGJ7	BHLH domain-containing protein.	AT-hook motif nuclear-localized protein; Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs).	0.511
A0A0K9Q2R8	ZOSMA_64G00560	A0A0K9Q2R8	A0A0K9NSS7	BHLH domain-containing protein.	BHLH domain-containing protein.	0.540
A0A0K9Q2R8	ZOSMA_64G00580	A0A0K9Q2R8	A0A0K9NSS8	BHLH domain-containing protein.	APRATAXIN-like.	0.540
ZOSMA_18G00430	A0A0K9Q2R8	A0A0K9PRV2	A0A0K9Q2R8	BHLH domain-containing protein.	BHLH domain-containing protein.	0.540
ZOSMA_18G00430	ZOSMA_26G01170	A0A0K9PRV2	A0A0K9PGJ7	BHLH domain-containing protein.	AT-hook motif nuclear-localized protein; Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs).	0.511
ZOSMA_18G00430	ZOSMA_64G00560	A0A0K9PRV2	A0A0K9NSS7	BHLH domain-containing protein.	BHLH domain-containing protein.	0.540
ZOSMA_18G00430	ZOSMA_64G00580	A0A0K9PRV2	A0A0K9NSS8	BHLH domain-containing protein.	APRATAXIN-like.	0.540
ZOSMA_26G01170	A0A0K9Q2R8	A0A0K9PGJ7	A0A0K9Q2R8	AT-hook motif nuclear-localized protein; Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs).	BHLH domain-containing protein.	0.511
ZOSMA_26G01170	ZOSMA_18G00430	A0A0K9PGJ7	A0A0K9PRV2	AT-hook motif nuclear-localized protein; Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs).	BHLH domain-containing protein.	0.511
ZOSMA_26G01170	ZOSMA_64G00560	A0A0K9PGJ7	A0A0K9NSS7	AT-hook motif nuclear-localized protein; Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs).	BHLH domain-containing protein.	0.511
ZOSMA_26G01170	ZOSMA_64G00580	A0A0K9PGJ7	A0A0K9NSS8	AT-hook motif nuclear-localized protein; Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs).	APRATAXIN-like.	0.420
ZOSMA_64G00560	A0A0K9Q2R8	A0A0K9NSS7	A0A0K9Q2R8	BHLH domain-containing protein.	BHLH domain-containing protein.	0.540
ZOSMA_64G00560	ZOSMA_18G00430	A0A0K9NSS7	A0A0K9PRV2	BHLH domain-containing protein.	BHLH domain-containing protein.	0.540
ZOSMA_64G00560	ZOSMA_26G01170	A0A0K9NSS7	A0A0K9PGJ7	BHLH domain-containing protein.	AT-hook motif nuclear-localized protein; Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs).	0.511
ZOSMA_64G00560	ZOSMA_64G00580	A0A0K9NSS7	A0A0K9NSS8	BHLH domain-containing protein.	APRATAXIN-like.	0.540
ZOSMA_64G00580	A0A0K9Q2R8	A0A0K9NSS8	A0A0K9Q2R8	APRATAXIN-like.	BHLH domain-containing protein.	0.540
ZOSMA_64G00580	ZOSMA_18G00430	A0A0K9NSS8	A0A0K9PRV2	APRATAXIN-like.	BHLH domain-containing protein.	0.540
ZOSMA_64G00580	ZOSMA_26G01170	A0A0K9NSS8	A0A0K9PGJ7	APRATAXIN-like.	AT-hook motif nuclear-localized protein; Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs).	0.420
ZOSMA_64G00580	ZOSMA_64G00560	A0A0K9NSS8	A0A0K9NSS7	APRATAXIN-like.	BHLH domain-containing protein.	0.540

Network Stats

number of nodes:

11

number of edges:

36

average node degree:

6.55

avg. local clustering coefficient:

0.715

expected number of edges:

36

PPI enrichment p-value:

0.514

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0007186

G protein-coupled receptor signaling pathway

6 of 131

1.92

2.98

1.77e-07

GO:0048312

Intracellular distribution of mitochondria

2 of 4

2.96

1.53

0.0017

GO:1902115

Regulation of organelle assembly

3 of 50

2.04

1.48

0.0013

GO:1900242

Regulation of synaptic vesicle endocytosis

2 of 5

2.87

1.48

0.0021

GO:0007154

Cell communication

9 of 1248

1.12

1.33

1.51e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030159

Signaling receptor complex adaptor activity

3 of 22

2.4

1.78

0.00047

GO:0001965

G-protein alpha-subunit binding

2 of 5

2.87

1.38

0.0032

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005834

Heterotrimeric G-protein complex

4 of 13

2.75

3.74

1.08e-07

GO:0044297

Cell body

2 of 26

2.15

1.18

0.0061

GO:0043195

Terminal bouton

2 of 23

2.2

1.18

0.0061

GO:0071944

Cell periphery

7 of 1721

0.87

0.74

0.00070

GO:0005770

Late endosome

2 of 83

1.65

0.69

0.0426

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:10680

GPCR ligand binding, and Regulation of G protein-coupled receptor signaling pathway

7 of 75

2.23

5.07

1.03e-11

CL:10782

RGS domain, and GTPase complex

5 of 20

2.66

4.96

3.29e-10

CL:10783

RGS domain, and GTPase complex

4 of 13

2.75

4.01

3.19e-08

CL:344

Intracellular distribution of mitochondria, and Immunoglobulin V-set domain

2 of 5

2.87

1.57

0.0014

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-418594

G alpha (i) signalling events

6 of 83

2.12

4.03

1.67e-09

MAP-372790

Signaling by GPCR

7 of 156

1.92

3.73

7.50e-10

MAP-373080

Class B/2 (Secretin family receptors)

3 of 4

3.14

3.25

1.25e-06

MAP-202040

G-protein activation

3 of 4

3.14

3.25

1.25e-06

MAP-397795

G-protein beta:gamma signalling

3 of 7

2.9

3.09

2.14e-06

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0098562

Cytoplasmic side of membrane

5 of 27

2.53

4.37

3.37e-09

GOCC:0005834

Heterotrimeric G-protein complex

3 of 11

2.7

2.73

8.88e-06

GOCC:0032473

Cytoplasmic side of mitochondrial outer membrane

2 of 2

3.26

2.12

0.00015

GOCC:0071944

Cell periphery

8 of 696

1.32

1.87

1.07e-07

GOCC:0005886

Plasma membrane

7 of 614

1.32

1.68

1.90e-06

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0853

WD repeat

3 of 130

1.63

0.96

0.0102

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR016346

Guanine nucleotide-binding protein, beta subunit

3 of 3

3.26

2.84

7.33e-06

IPR001632

G-protein, beta subunit

2 of 2

3.26

1.45

0.0025

IPR019775

WD40 repeat, conserved site

3 of 65

1.93

1.14

0.0060

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00320

WD40 repeats

3 of 161

1.53

0.73

0.0327

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