node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DHFR-TS | FOLD | C1E6F7 | C1FDF4 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 5,10-methylene-tetrahydrofolate dehydrogenase/cyclohydrolase. | 0.938 |
DHFR-TS | GCSH | C1E6F7 | C1E2M0 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.931 |
DHFR-TS | GCSP | C1E6F7 | C1E9T7 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.931 |
DHFR-TS | GCST | C1E6F7 | C1E9Q6 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.991 |
DHFR-TS | MICPUN_55714 | C1E6F7 | C1DZ51 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Phosphoribosylglycinamide formyltransferase. | 0.984 |
DHFR-TS | MICPUN_57207 | C1E6F7 | C1E2E2 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Uncharacterized protein. | 0.920 |
DHFR-TS | MICPUN_59938 | C1E6F7 | C1EA40 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Aldedh domain-containing protein. | 0.896 |
DHFR-TS | MICPUN_69926 | C1E6F7 | C1FGW2 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Uncharacterized protein. | 0.992 |
DHFR-TS | MICPUN_87614 | C1E6F7 | C1EFA3 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.751 |
DHFR-TS | MICPUN_93776 | C1E6F7 | C1E2J7 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Uncharacterized protein. | 0.996 |
FOLD | DHFR-TS | C1FDF4 | C1E6F7 | 5,10-methylene-tetrahydrofolate dehydrogenase/cyclohydrolase. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.938 |
FOLD | GCSH | C1FDF4 | C1E2M0 | 5,10-methylene-tetrahydrofolate dehydrogenase/cyclohydrolase. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.820 |
FOLD | GCSP | C1FDF4 | C1E9T7 | 5,10-methylene-tetrahydrofolate dehydrogenase/cyclohydrolase. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.841 |
FOLD | GCST | C1FDF4 | C1E9Q6 | 5,10-methylene-tetrahydrofolate dehydrogenase/cyclohydrolase. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.759 |
FOLD | MICPUN_55714 | C1FDF4 | C1DZ51 | 5,10-methylene-tetrahydrofolate dehydrogenase/cyclohydrolase. | Phosphoribosylglycinamide formyltransferase. | 0.821 |
FOLD | MICPUN_57207 | C1FDF4 | C1E2E2 | 5,10-methylene-tetrahydrofolate dehydrogenase/cyclohydrolase. | Uncharacterized protein. | 0.759 |
FOLD | MICPUN_59938 | C1FDF4 | C1EA40 | 5,10-methylene-tetrahydrofolate dehydrogenase/cyclohydrolase. | Aldedh domain-containing protein. | 0.789 |
FOLD | MICPUN_69926 | C1FDF4 | C1FGW2 | 5,10-methylene-tetrahydrofolate dehydrogenase/cyclohydrolase. | Uncharacterized protein. | 0.775 |
FOLD | MICPUN_87614 | C1FDF4 | C1EFA3 | 5,10-methylene-tetrahydrofolate dehydrogenase/cyclohydrolase. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.795 |
FOLD | MICPUN_93776 | C1FDF4 | C1E2J7 | 5,10-methylene-tetrahydrofolate dehydrogenase/cyclohydrolase. | Uncharacterized protein. | 0.979 |