node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bpro_0002 | Bpro_0216 | Bpro_0002 | Bpro_0216 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III (xth). | 0.657 |
Bpro_0002 | Bpro_1299 | Bpro_0002 | Bpro_1299 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.515 |
Bpro_0002 | Bpro_1820 | Bpro_0002 | Bpro_1820 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III. | 0.657 |
Bpro_0002 | Bpro_3424 | Bpro_0002 | Bpro_3424 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III. | 0.657 |
Bpro_0002 | polA | Bpro_0002 | Bpro_1729 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.983 |
Bpro_0002 | ung | Bpro_0002 | Bpro_4450 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.667 |
Bpro_0216 | Bpro_0002 | Bpro_0216 | Bpro_0002 | Exodeoxyribonuclease III (xth). | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.657 |
Bpro_0216 | Bpro_0218 | Bpro_0216 | Bpro_0218 | Exodeoxyribonuclease III (xth). | Conserved hypothetical protein. | 0.606 |
Bpro_0216 | Bpro_1299 | Bpro_0216 | Bpro_1299 | Exodeoxyribonuclease III (xth). | A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.656 |
Bpro_0216 | Bpro_1638 | Bpro_0216 | Bpro_1638 | Exodeoxyribonuclease III (xth). | DNA-3-methyladenine glycosylase II / DNA-O6-methylguanine--protein-cysteine S-methyltransferase. | 0.663 |
Bpro_0216 | Bpro_1820 | Bpro_0216 | Bpro_1820 | Exodeoxyribonuclease III (xth). | Exodeoxyribonuclease III. | 0.930 |
Bpro_0216 | Bpro_3424 | Bpro_0216 | Bpro_3424 | Exodeoxyribonuclease III (xth). | Exodeoxyribonuclease III. | 0.930 |
Bpro_0216 | nth | Bpro_0216 | Bpro_2747 | Exodeoxyribonuclease III (xth). | Endonuclease III / DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.951 |
Bpro_0216 | polA | Bpro_0216 | Bpro_1729 | Exodeoxyribonuclease III (xth). | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.734 |
Bpro_0216 | pyrE | Bpro_0216 | Bpro_0217 | Exodeoxyribonuclease III (xth). | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.659 |
Bpro_0216 | ung | Bpro_0216 | Bpro_4450 | Exodeoxyribonuclease III (xth). | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.578 |
Bpro_0218 | Bpro_0216 | Bpro_0218 | Bpro_0216 | Conserved hypothetical protein. | Exodeoxyribonuclease III (xth). | 0.606 |
Bpro_0218 | pyrE | Bpro_0218 | Bpro_0217 | Conserved hypothetical protein. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.797 |
Bpro_1299 | Bpro_0002 | Bpro_1299 | Bpro_0002 | A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.515 |
Bpro_1299 | Bpro_0216 | Bpro_1299 | Bpro_0216 | A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Exodeoxyribonuclease III (xth). | 0.656 |