STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Belongs to the pseudomonas-type ThrB family. (316 aa)    
Predicted Functional Partners:
Bpro_2190
Homoserine dehydrogenase.
 
  
 0.934
Bpro_2191
L-threonine synthase.
    
 0.920
ilvE
Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.818
Bpro_1836
O-acetylhomoserine sulfhydrolase.
    
  0.805
Bpro_3388
Methionine synthase, vitamin-B12 independent.
     
 0.804
Bpro_3466
Methionine synthase (B12-independent).
     
 0.804
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
  0.803
Bpro_0172
Methionine synthase (B12-dependent).
    
  0.801
Bpro_0174
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.801
Bpro_2830
Cystathionine beta-synthase.
    
  0.801
Your Current Organism:
Polaromonas sp. JS666
NCBI taxonomy Id: 296591
Other names: P. sp. JS666
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.