| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bpro_0002 | Bpro_2387 | Bpro_0002 | Bpro_2387 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Conserved hypothetical protein. | 0.815 |
| Bpro_0002 | Bpro_2518 | Bpro_0002 | Bpro_2518 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed DNA polymerase. | 0.995 |
| Bpro_0002 | Bpro_3003 | Bpro_0002 | Bpro_3003 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA ligase LigD polymerase module. | 0.879 |
| Bpro_0002 | Bpro_3424 | Bpro_0002 | Bpro_3424 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III. | 0.735 |
| Bpro_0002 | polA | Bpro_0002 | Bpro_1729 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.969 |
| Bpro_2306 | Bpro_3003 | Bpro_2306 | Bpro_3003 | Protein of unknown function DUF1452. | ATP-dependent DNA ligase LigD polymerase module. | 0.553 |
| Bpro_2306 | ku | Bpro_2306 | Bpro_3002 | Protein of unknown function DUF1452. | Conserved hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.407 |
| Bpro_2387 | Bpro_0002 | Bpro_2387 | Bpro_0002 | Conserved hypothetical protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.815 |
| Bpro_2387 | Bpro_2518 | Bpro_2387 | Bpro_2518 | Conserved hypothetical protein. | DNA-directed DNA polymerase. | 0.486 |
| Bpro_2387 | Bpro_3003 | Bpro_2387 | Bpro_3003 | Conserved hypothetical protein. | ATP-dependent DNA ligase LigD polymerase module. | 0.557 |
| Bpro_2387 | polA | Bpro_2387 | Bpro_1729 | Conserved hypothetical protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.671 |
| Bpro_2453 | Bpro_3003 | Bpro_2453 | Bpro_3003 | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | ATP-dependent DNA ligase LigD polymerase module. | 0.630 |
| Bpro_2453 | ku | Bpro_2453 | Bpro_3002 | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | Conserved hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.561 |
| Bpro_2518 | Bpro_0002 | Bpro_2518 | Bpro_0002 | DNA-directed DNA polymerase. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.995 |
| Bpro_2518 | Bpro_2387 | Bpro_2518 | Bpro_2387 | DNA-directed DNA polymerase. | Conserved hypothetical protein. | 0.486 |
| Bpro_2518 | Bpro_3003 | Bpro_2518 | Bpro_3003 | DNA-directed DNA polymerase. | ATP-dependent DNA ligase LigD polymerase module. | 0.551 |
| Bpro_2518 | polA | Bpro_2518 | Bpro_1729 | DNA-directed DNA polymerase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.867 |
| Bpro_3003 | Bpro_0002 | Bpro_3003 | Bpro_0002 | ATP-dependent DNA ligase LigD polymerase module. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.879 |
| Bpro_3003 | Bpro_2306 | Bpro_3003 | Bpro_2306 | ATP-dependent DNA ligase LigD polymerase module. | Protein of unknown function DUF1452. | 0.553 |
| Bpro_3003 | Bpro_2387 | Bpro_3003 | Bpro_2387 | ATP-dependent DNA ligase LigD polymerase module. | Conserved hypothetical protein. | 0.557 |