Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Bpro_4191Phenylacetic acid degradation-related protein. (124 aa)    
Predicted Functional Partners:
Bpro_0604
AMP-dependent synthetase and ligase.
 
   
 0.642
Bpro_4190
isovaleryl-CoA dehydrogenase.
  
  
 0.604
Bpro_0598
Putative phenylacetate-CoA ligase.
 
  
 0.601
Bpro_2566
Phenylacetic acid degradation-related protein.
 
     0.552
Bpro_0600
Amino acid/amide ABC transporter substrate-binding protein, HAAT family; TC 3.A.1.4.-.
  
     0.545
Bpro_0601
Amino acid/amide ABC transporter membrane protein 2, HAAT family; TC 3.A.1.4.-; Belongs to the binding-protein-dependent transport system permease family.
 
     0.505
Bpro_4189
Carbonate dehydratase.
       0.495
Bpro_4192
Transcriptional regulator, MerR family.
  
    0.495
Bpro_0599
Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; TC 3.A.1.4.-.
 
     0.446
aceK
(Isocitrate dehydrogenase (NADP+)) kinase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
       0.445
Your Current Organism:
Polaromonas sp. JS666
NCBI taxonomy Id: 296591
Other names: P. sp. JS666
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