kbl protein (Polaromonas sp. JS666) - STRING interaction network

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kbl

2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (400 aa)

Predicted Functional Partners:

Bpro_4367

0.966

gcvP

0.939

glyA

0.915

Bpro_2069

0.906

Bpro_4454

0.906

Bpro_0548

0.903

Bpro_2753

0.903

bioD

0.808

Bpro_3393

0.693

Bpro_4365

0.630

Your Current Organism:

Polaromonas sp. JS666

NCBI taxonomy Id: 296591
Other names: P. sp. JS666

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bpro_0548	Bpro_2069	Bpro_0548	Bpro_2069	Serine--glyoxylate transaminase.	L-threonine aldolase.	0.905
Bpro_0548	Bpro_2753	Bpro_0548	Bpro_2753	Serine--glyoxylate transaminase.	Aminotransferase, class V.	0.901
Bpro_0548	Bpro_4454	Bpro_0548	Bpro_4454	Serine--glyoxylate transaminase.	L-threonine aldolase.	0.905
Bpro_0548	gcvP	Bpro_0548	Bpro_1866	Serine--glyoxylate transaminase.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.913
Bpro_0548	glyA	Bpro_0548	Bpro_2874	Serine--glyoxylate transaminase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.917
Bpro_0548	kbl	Bpro_0548	Bpro_4366	Serine--glyoxylate transaminase.	2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.	0.903
Bpro_2069	Bpro_0548	Bpro_2069	Bpro_0548	L-threonine aldolase.	Serine--glyoxylate transaminase.	0.905
Bpro_2069	Bpro_2753	Bpro_2069	Bpro_2753	L-threonine aldolase.	Aminotransferase, class V.	0.905
Bpro_2069	Bpro_4454	Bpro_2069	Bpro_4454	L-threonine aldolase.	L-threonine aldolase.	0.918
Bpro_2069	gcvP	Bpro_2069	Bpro_1866	L-threonine aldolase.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.947
Bpro_2069	glyA	Bpro_2069	Bpro_2874	L-threonine aldolase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.928
Bpro_2069	kbl	Bpro_2069	Bpro_4366	L-threonine aldolase.	2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.	0.906
Bpro_2753	Bpro_0548	Bpro_2753	Bpro_0548	Aminotransferase, class V.	Serine--glyoxylate transaminase.	0.901
Bpro_2753	Bpro_2069	Bpro_2753	Bpro_2069	Aminotransferase, class V.	L-threonine aldolase.	0.905
Bpro_2753	Bpro_4454	Bpro_2753	Bpro_4454	Aminotransferase, class V.	L-threonine aldolase.	0.905
Bpro_2753	gcvP	Bpro_2753	Bpro_1866	Aminotransferase, class V.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.913
Bpro_2753	glyA	Bpro_2753	Bpro_2874	Aminotransferase, class V.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.917
Bpro_2753	kbl	Bpro_2753	Bpro_4366	Aminotransferase, class V.	2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.	0.903
Bpro_3393	bioD	Bpro_3393	Bpro_0899	AMP-dependent synthetase and ligase.	Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.414
Bpro_3393	gcvP	Bpro_3393	Bpro_1866	AMP-dependent synthetase and ligase.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.429