STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIS41247.1Bifunctional non-homologous end joining protein LigD. (623 aa)    
Predicted Functional Partners:
SIS41241.1
Bifunctional non-homologous end joining protein LigD.
  
 0.999
ku
DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.977
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.964
dnaN_2
DNA polymerase-3 subunit beta.
   
 0.948
sbcC_2
Exonuclease SbcC.
   
 0.803
hisB
Imidazoleglycerol-phosphate dehydratase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
   
 0.778
SIS28287.1
Putative mRNA 3-end processing factor.
 
 
 0.699
lepB
Signal peptidase I; Belongs to the peptidase S26 family.
    
  0.682
SIS30694.1
DNA topoisomerase-1.
 
 
 
 0.657
SIS28308.1
BRCA1 C Terminus (BRCT) domain-containing protein.
     
 0.645
Your Current Organism:
Chryseobacterium shigense
NCBI taxonomy Id: 297244
Other names: C. shigense, Chryseobacterium shigense Shimomura et al. 2005 emend. Montero-Calasanz et al. 2014, Chryseobacterium sp. 1107B-08, Chryseobacterium sp. 628-2-08, Chryseobacterium sp. 664-09, Chryseobacterium sp. 972B-08, DSM 17126, NCIMB 14047, strain GUM-Kaji
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.