STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D7TU01_VITVIMHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (438 aa)    
Predicted Functional Partners:
D7SN66_VITVI
AP-2 complex subunit alpha; Subunit of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome.
   
 0.994
D7SP01_VITVI
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
  
 0.988
E0CQ54_VITVI
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
  
 0.988
D7SUE8_VITVI
Beta-adaptin-like protein; Subunit of clathrin-associated adaptor protein complex that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
   
 0.892
D7TV41_VITVI
Beta-adaptin-like protein; Subunit of clathrin-associated adaptor protein complex that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
   
 0.892
VITISV_002501
DUF1681 domain-containing protein.
    
 0.873
E0CTP8_VITVI
DUF1681 domain-containing protein.
    
 0.873
F6GXI4_VITVI
Uncharacterized protein.
   
 0.862
D7TFY3_VITVI
Adaptin_N domain-containing protein.
   
 0.839
F6GXG7_VITVI
MHD domain-containing protein.
   
 0.827
Your Current Organism:
Vitis vinifera
NCBI taxonomy Id: 29760
Other names: V. vinifera, Vitis vinifera L., Vitis vinifera subsp. vinifera, wine grape
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