STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F6H1W5_VITVIFolate gamma-glutamyl hydrolase. (384 aa)    
Predicted Functional Partners:
F6H1I8_VITVI
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
   
 
 0.968
F6I0M2_VITVI
DHFR domain-containing protein.
   
 
 0.968
F6HLM9_VITVI
SAP domain-containing protein.
     
 0.935
F6HNT5_VITVI
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
     
 0.935
F6GYC9_VITVI
DHFR domain-containing protein.
   
  
 0.695
PURA
Adenylosuccinate synthetase, chloroplastic; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
      
 0.638
D7SND0_VITVI
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
      
 0.579
E0CUK0_VITVI
Mur_ligase_M domain-containing protein.
      
 0.564
VITISV_012640
Uncharacterized protein.
   
  
 0.563
D7TLX6_VITVI
Uncharacterized protein; Belongs to the universal ribosomal protein uS8 family.
      
 0.555
Your Current Organism:
Vitis vinifera
NCBI taxonomy Id: 29760
Other names: V. vinifera, Vitis vinifera L., Vitis vinifera subsp. vinifera, wine grape
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