STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F6HLM9_VITVISAP domain-containing protein. (1717 aa)    
Predicted Functional Partners:
F6H1I8_VITVI
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
     
 0.989
F6I0M2_VITVI
DHFR domain-containing protein.
     
 0.989
F6HEZ6_VITVI
Pterin-binding domain-containing protein.
  
 
 0.988
F6H1W5_VITVI
Folate gamma-glutamyl hydrolase.
     
 0.935
E0CUK0_VITVI
Mur_ligase_M domain-containing protein.
     
0.933
F6HNT5_VITVI
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
  
  
 
0.901
F6GYC9_VITVI
DHFR domain-containing protein.
     
 0.896
F6HZT1_VITVI
7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
 
 0.866
F6GUF4_VITVI
Uncharacterized protein.
  
 
 0.823
D7T9B5_VITVI
Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.
  
 
 0.757
Your Current Organism:
Vitis vinifera
NCBI taxonomy Id: 29760
Other names: V. vinifera, Vitis vinifera L., Vitis vinifera subsp. vinifera, wine grape
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.