F6HYL4_VITVI protein (Vitis vinifera) - STRING interaction network

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

F6HYL4_VITVI

Uncharacterized protein. (288 aa)

Predicted Functional Partners:

F6GU63_VITVI

0.912

D7SQB0_VITVI

0.863

D7SU26_VITVI

0.863

D7TS99_VITVI

0.766

D7TVE8_VITVI

0.757

F6H4J7_VITVI

0.753

D7TAP9_VITVI

0.694

F6HLJ1_VITVI

0.694

F6GVH0_VITVI

0.691

F6HE88_VITVI

0.606

Your Current Organism:

Vitis vinifera

NCBI taxonomy Id: 29760
Other names: V. vinifera, Vitis vinifera L., Vitis vinifera subsp. vinifera, wine grape

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D7SQB0_VITVI	D7SU26_VITVI	D7SQB0	D7SU26	Uncharacterized protein.	RPA_C domain-containing protein.	0.902
D7SQB0_VITVI	D7TAP9_VITVI	D7SQB0	D7TAP9	Uncharacterized protein.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.962
D7SQB0_VITVI	D7TS99_VITVI	D7SQB0	D7TS99	Uncharacterized protein.	Uncharacterized protein.	0.975
D7SQB0_VITVI	D7TVE8_VITVI	D7SQB0	D7TVE8	Uncharacterized protein.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.971
D7SQB0_VITVI	F6GU63_VITVI	D7SQB0	F6GU63	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.965
D7SQB0_VITVI	F6GVH0_VITVI	D7SQB0	F6GVH0	Uncharacterized protein.	Uncharacterized protein.	0.911
D7SQB0_VITVI	F6H4J7_VITVI	D7SQB0	F6H4J7	Uncharacterized protein.	DNA polymerase.	0.963
D7SQB0_VITVI	F6HE88_VITVI	D7SQB0	F6HE88	Uncharacterized protein.	Uncharacterized protein.	0.734
D7SQB0_VITVI	F6HLJ1_VITVI	D7SQB0	F6HLJ1	Uncharacterized protein.	Uncharacterized protein.	0.890
D7SQB0_VITVI	F6HYL4_VITVI	D7SQB0	F6HYL4	Uncharacterized protein.	Uncharacterized protein.	0.863
D7SU26_VITVI	D7SQB0_VITVI	D7SU26	D7SQB0	RPA_C domain-containing protein.	Uncharacterized protein.	0.902
D7SU26_VITVI	D7TAP9_VITVI	D7SU26	D7TAP9	RPA_C domain-containing protein.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.962
D7SU26_VITVI	D7TS99_VITVI	D7SU26	D7TS99	RPA_C domain-containing protein.	Uncharacterized protein.	0.975
D7SU26_VITVI	D7TVE8_VITVI	D7SU26	D7TVE8	RPA_C domain-containing protein.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.971
D7SU26_VITVI	F6GU63_VITVI	D7SU26	F6GU63	RPA_C domain-containing protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.965
D7SU26_VITVI	F6GVH0_VITVI	D7SU26	F6GVH0	RPA_C domain-containing protein.	Uncharacterized protein.	0.911
D7SU26_VITVI	F6H4J7_VITVI	D7SU26	F6H4J7	RPA_C domain-containing protein.	DNA polymerase.	0.963
D7SU26_VITVI	F6HE88_VITVI	D7SU26	F6HE88	RPA_C domain-containing protein.	Uncharacterized protein.	0.734
D7SU26_VITVI	F6HLJ1_VITVI	D7SU26	F6HLJ1	RPA_C domain-containing protein.	Uncharacterized protein.	0.890
D7SU26_VITVI	F6HYL4_VITVI	D7SU26	F6HYL4	RPA_C domain-containing protein.	Uncharacterized protein.	0.863

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

24

average node degree:

4.36

avg. local clustering coefficient:

0.856

expected number of edges:

33

PPI enrichment p-value:

0.959

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2713

Alpha/beta hydrolase fold-1

4 of 6

2.57

3.35

1.13e-06

CL:1085

Phosphopantetheine attachment site, and Thioesterase domain

2 of 10

2.04

0.79

0.0417

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031975

Envelope

4 of 85

1.42

1.1

0.0033

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0596

Phosphopantetheine

3 of 47

1.55

0.9

0.0158

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00561

Alpha/beta hydrolase fold

3 of 22

1.88

1.19

0.0061

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000073

Alpha/beta hydrolase fold-1

4 of 22

2.0

2.04

0.00012

IPR032821

Polyketide synthase, C-terminal extension

3 of 16

2.02

1.4

0.0028

IPR013968

Polyketide synthase, ketoreductase domain

3 of 15

2.04

1.4

0.0028

IPR016036

Malonyl-CoA ACP transacylase, ACP-binding

3 of 17

1.99

1.39

0.0028

IPR014043

Acyl transferase

3 of 17

1.99

1.39

0.0028

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00822

This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group.

3 of 13

2.11

1.88

0.00034

SM00827

Acyl transferase domain in polyketide synthase (PKS) enzymes.

3 of 15

2.04

1.85

0.00034

SM00823

Phosphopantetheine attachment site

3 of 16

2.02

1.84

0.00034

SM00826

PKS_DH

2 of 4

2.44

1.61

0.0016

SM00825

Beta-ketoacyl synthase

2 of 12

1.96

1.16

0.0078

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