STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AWRI3580_g1858Putative DNA helicase INO80. (1411 aa)    
Predicted Functional Partners:
AWRI3580_g1384
Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family.
    
  0.966
AWRI3580_g3645
RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
    
 0.955
AWRI3580_g2201
RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
    
 0.933
AWRI3580_g2953
Actin-related protein 4; Belongs to the actin family.
    
 0.932
AWRI3580_g3351
Actin.
    
  0.904
AWRI3580_g1740
Actin-related protein 5; Belongs to the actin family.
    
 0.892
AWRI3580_g3586
Histone H2B.2; Belongs to the histone H2B family.
    
 0.781
AWRI3580_g3587
Histone H2A; Belongs to the histone H2A family.
    
 0.748
AWRI3580_g1841
Histone H3; Belongs to the histone H3 family.
    
 0.730
AWRI3580_g1842
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.727
Your Current Organism:
Hanseniaspora uvarum
NCBI taxonomy Id: 29833
Other names: ATCC 32369, CBS 314, DBVPG 6718, H. uvarum, Hanseniaspora apiculata, IFO 10833, Kloeckera apiculata, Kloeckeraspora uvarum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.