node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AWRI3580_g109 | AWRI3580_g1184 | A0A1E5S1G1 | A0A1E5RUU9 | DNA replication ATP-dependent helicase/nuclease DNA2. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.790 |
AWRI3580_g109 | AWRI3580_g1254 | A0A1E5S1G1 | A0A1E5RUS0 | DNA replication ATP-dependent helicase/nuclease DNA2. | DNA repair protein RAD1. | 0.600 |
AWRI3580_g109 | AWRI3580_g1256 | A0A1E5S1G1 | A0A1E5RUX6 | DNA replication ATP-dependent helicase/nuclease DNA2. | RMI1_N domain-containing protein. | 0.734 |
AWRI3580_g109 | AWRI3580_g1530 | A0A1E5S1G1 | A0A1E5RUP7 | DNA replication ATP-dependent helicase/nuclease DNA2. | Crossover junction endonuclease MUS81. | 0.776 |
AWRI3580_g109 | AWRI3580_g2125 | A0A1E5S1G1 | A0A1E5RQL4 | DNA replication ATP-dependent helicase/nuclease DNA2. | ATP-dependent helicase SGS1. | 0.939 |
AWRI3580_g109 | AWRI3580_g2483 | A0A1E5S1G1 | A0A1E5RJU0 | DNA replication ATP-dependent helicase/nuclease DNA2. | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. | 0.784 |
AWRI3580_g109 | AWRI3580_g2555 | A0A1E5S1G1 | A0A1E5RIK2 | DNA replication ATP-dependent helicase/nuclease DNA2. | Exodeoxyribonuclease 1. | 0.905 |
AWRI3580_g109 | AWRI3580_g2925 | A0A1E5S1G1 | A0A1E5RIP0 | DNA replication ATP-dependent helicase/nuclease DNA2. | ATP-dependent DNA helicase SRS2. | 0.448 |
AWRI3580_g109 | AWRI3580_g3800 | A0A1E5S1G1 | A0A1E5R6X4 | DNA replication ATP-dependent helicase/nuclease DNA2. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.950 |
AWRI3580_g109 | AWRI3580_g3845 | A0A1E5S1G1 | A0A1E5R458 | DNA replication ATP-dependent helicase/nuclease DNA2. | ATP-dependent DNA helicase MPH1. | 0.494 |
AWRI3580_g1184 | AWRI3580_g109 | A0A1E5RUU9 | A0A1E5S1G1 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DNA replication ATP-dependent helicase/nuclease DNA2. | 0.790 |
AWRI3580_g1184 | AWRI3580_g1254 | A0A1E5RUU9 | A0A1E5RUS0 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DNA repair protein RAD1. | 0.956 |
AWRI3580_g1184 | AWRI3580_g1256 | A0A1E5RUU9 | A0A1E5RUX6 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | RMI1_N domain-containing protein. | 0.981 |
AWRI3580_g1184 | AWRI3580_g1530 | A0A1E5RUU9 | A0A1E5RUP7 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Crossover junction endonuclease MUS81. | 0.921 |
AWRI3580_g1184 | AWRI3580_g2125 | A0A1E5RUU9 | A0A1E5RQL4 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | ATP-dependent helicase SGS1. | 0.996 |
AWRI3580_g1184 | AWRI3580_g2483 | A0A1E5RUU9 | A0A1E5RJU0 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. | 0.838 |
AWRI3580_g1184 | AWRI3580_g2555 | A0A1E5RUU9 | A0A1E5RIK2 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Exodeoxyribonuclease 1. | 0.785 |
AWRI3580_g1184 | AWRI3580_g2925 | A0A1E5RUU9 | A0A1E5RIP0 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | ATP-dependent DNA helicase SRS2. | 0.749 |
AWRI3580_g1184 | AWRI3580_g3800 | A0A1E5RUU9 | A0A1E5R6X4 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.977 |
AWRI3580_g1184 | AWRI3580_g3845 | A0A1E5RUU9 | A0A1E5R458 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | ATP-dependent DNA helicase MPH1. | 0.937 |