STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AWRI3580_g781tRNA (Carboxymethyluridine(34)-5-O)-methyltransferase. (323 aa)    
Predicted Functional Partners:
AWRI3580_g683
Multifunctional methyltransferase subunit TRM112.
   
 0.903
AWRI3580_g1441
20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.
   
 0.700
AWRI3580_g125
Ribosome biogenesis protein TSR1.
   
  0.620
AWRI3580_g1842
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.611
AWRI3580_g3455
Squalene synthase.
    
 0.607
AWRI3580_g2095
Essential nuclear protein 1.
   
 0.600
AWRI3580_g1379
Pre-rRNA-processing protein PNO1.
   
  0.595
AWRI3580_g2802
40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family.
    
  0.582
AWRI3580_g3978
37S ribosomal protein S5, mitochondrial; Belongs to the universal ribosomal protein uS5 family.
    
 0.578
AWRI3580_g2478
40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family.
    
  0.578
Your Current Organism:
Hanseniaspora uvarum
NCBI taxonomy Id: 29833
Other names: ATCC 32369, CBS 314, DBVPG 6718, H. uvarum, Hanseniaspora apiculata, IFO 10833, Kloeckera apiculata, Kloeckeraspora uvarum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.