node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C4475 | GMK | PBPRA0189 | PBPRA0191 | Putative guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.968 |
C4475 | PLU1372 | PBPRA0189 | PBPRA0759 | Putative guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Putative nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.923 |
C4475 | Y1944 | PBPRA0189 | PBPRA0428 | Putative guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Putative pyruvate kinase I; Predicted by orpheus program; predicted by glimmer program; Belongs to the pyruvate kinase family. | 0.902 |
C4475 | rpoZ | PBPRA0189 | PBPRA0190 | Putative guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Putative DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.812 |
GMK | C4475 | PBPRA0191 | PBPRA0189 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.968 |
GMK | PBPRA1638 | PBPRA0191 | PBPRA1638 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.937 |
GMK | PLU1241 | PBPRA0191 | PBPRA0836 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.960 |
GMK | PLU1372 | PBPRA0191 | PBPRA0759 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.934 |
GMK | S0103 | PBPRA0191 | PBPRB1716 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.928 |
GMK | S0421 | PBPRA0191 | PBPRA1016 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.960 |
GMK | T0175 | PBPRA0191 | PBPRA3180 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative hypoxanthine ribosyl transferase; Predicted by orpheus program; predicted by glimmer program; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.936 |
GMK | Y1944 | PBPRA0191 | PBPRA0428 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative pyruvate kinase I; Predicted by orpheus program; predicted by glimmer program; Belongs to the pyruvate kinase family. | 0.935 |
GMK | guaA | PBPRA0191 | PBPRA0781 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.963 |
GMK | rpoZ | PBPRA0191 | PBPRA0190 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.966 |
PBPRA1638 | GMK | PBPRA1638 | PBPRA0191 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.937 |
PBPRA1638 | PLU1241 | PBPRA1638 | PBPRA0836 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.928 |
PBPRA1638 | S0103 | PBPRA1638 | PBPRB1716 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.915 |
PBPRA1638 | S0421 | PBPRA1638 | PBPRA1016 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.928 |
PBPRA1638 | T0175 | PBPRA1638 | PBPRA3180 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative hypoxanthine ribosyl transferase; Predicted by orpheus program; predicted by glimmer program; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.924 |
PBPRA1638 | guaA | PBPRA1638 | PBPRA0781 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.941 |