| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GMK | LEPA | PBPRA0191 | PBPRA3091 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.581 |
| GMK | METG | PBPRA0191 | PBPRA1168 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.613 |
| GMK | STM4564 | PBPRA0191 | PBPRA0628 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.429 |
| HD0887 | STM4564 | PBPRA0629 | PBPRA0628 | Putative NupC family protein; Predicted by orpheus program; predicted by glimmer program; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.500 |
| LEPA | GMK | PBPRA3091 | PBPRA0191 | Putative GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.581 |
| LEPA | METG | PBPRA3091 | PBPRA1168 | Putative GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Putative methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.566 |
| LEPA | SF3105 | PBPRA3091 | PBPRA0434 | Putative GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.672 |
| LEPA | STM4564 | PBPRA3091 | PBPRA0628 | Putative GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.429 |
| METG | GMK | PBPRA1168 | PBPRA0191 | Putative methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.613 |
| METG | LEPA | PBPRA1168 | PBPRA3091 | Putative methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Putative GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.566 |
| METG | SF3105 | PBPRA1168 | PBPRA0434 | Putative methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.646 |
| METG | SSB | PBPRA1168 | PBPRA3289 | Putative methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Putative single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.619 |
| METG | STM4564 | PBPRA1168 | PBPRA0628 | Putative methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.481 |
| PBPRA1512 | STM4564 | PBPRA1512 | PBPRA0628 | Hypothetical esterase of the alpha-betahydrolase superfamily; Predicted by orpheus program; predicted by glimmer program. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.532 |
| PMT1397 | STM4564 | PBPRA0627 | PBPRA0628 | Putative glycogen operon protein; Predicted by orpheus program; predicted by glimmer program; Belongs to the glycosyl hydrolase 13 family. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.508 |
| S4680 | STM4564 | PBPRB1932 | PBPRA0628 | Conserved hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.532 |
| SF3105 | LEPA | PBPRA0434 | PBPRA3091 | Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Putative GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.672 |
| SF3105 | METG | PBPRA0434 | PBPRA1168 | Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Putative methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.646 |
| SF3105 | STM4564 | PBPRA0434 | PBPRA0628 | Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.492 |
| SSB | METG | PBPRA3289 | PBPRA1168 | Putative single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | Putative methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.619 |