STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPNKPutative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (293 aa)    
Predicted Functional Partners:
VVA0411
Conserved hypothetical protein; Predicted by orpheus program; predicted by glimmer program; Belongs to the NadD family.
  
 
 0.935
NADE
Putative NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
    
 0.933
VV1691
Putative NAD-dependent protein deacetylase; Predicted by orpheus program; predicted by glimmer program; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.925
SF1624
Putative NAD(P) transhydrogenase, alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.
     
 0.923
STHA
Putative pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
     
 0.910
PLU2168
Putative NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.910
STY3083
Putative MazG protein; Predicted by orpheus program; predicted by glimmer program.
     
 0.903
S3667
Putative MutT/nudix family protein; Predicted by orpheus program; predicted by glimmer program.
     
 0.903
dxs
Putative deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
    
 0.661
C3138
Putative DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
  
 0.642
Your Current Organism:
Photobacterium profundum
NCBI taxonomy Id: 298386
Other names: P. profundum SS9, Photobacterium SS9, Photobacterium profundum SS9, Photobacterium profundum str. SS9, Photobacterium profundum strain SS9, Photobacterium sp. (strain SS9), Photobacterium sp. SS9, deep-sea eubacterium SS9
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