| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C3138 | PLU3372 | PBPRA0694 | PBPRA0696 | Putative DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Putative heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several round [...] | 0.670 |
| C3138 | PPNK | PBPRA0694 | PBPRA0695 | Putative DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.720 |
| NADE | PLU2168 | PBPRB0911 | PBPRB0903 | Putative NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Putative NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.911 |
| NADE | PPNK | PBPRB0911 | PBPRA0695 | Putative NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.937 |
| NADE | S3667 | PBPRB0911 | PBPRA3429 | Putative NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Putative MutT/nudix family protein; Predicted by orpheus program; predicted by glimmer program. | 0.905 |
| NADE | SF1624 | PBPRB0911 | PBPRB0902 | Putative NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Putative NAD(P) transhydrogenase, alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.904 |
| NADE | STHA | PBPRB0911 | PBPRA3468 | Putative NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Putative pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.902 |
| NADE | STY3083 | PBPRB0911 | PBPRA3081 | Putative NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Putative MazG protein; Predicted by orpheus program; predicted by glimmer program. | 0.900 |
| NADE | VV1691 | PBPRB0911 | PBPRA1859 | Putative NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Putative NAD-dependent protein deacetylase; Predicted by orpheus program; predicted by glimmer program; Belongs to the sirtuin family. Class III subfamily. | 0.931 |
| NADE | VVA0411 | PBPRB0911 | PBPRB0912 | Putative NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Conserved hypothetical protein; Predicted by orpheus program; predicted by glimmer program; Belongs to the NadD family. | 0.973 |
| PLU2168 | NADE | PBPRB0903 | PBPRB0911 | Putative NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Putative NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.911 |
| PLU2168 | PPNK | PBPRB0903 | PBPRA0695 | Putative NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.910 |
| PLU2168 | S3667 | PBPRB0903 | PBPRA3429 | Putative NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Putative MutT/nudix family protein; Predicted by orpheus program; predicted by glimmer program. | 0.900 |
| PLU2168 | SF1624 | PBPRB0903 | PBPRB0902 | Putative NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Putative NAD(P) transhydrogenase, alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.999 |
| PLU2168 | STHA | PBPRB0903 | PBPRA3468 | Putative NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Putative pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.924 |
| PLU2168 | STY3083 | PBPRB0903 | PBPRA3081 | Putative NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Putative MazG protein; Predicted by orpheus program; predicted by glimmer program. | 0.903 |
| PLU2168 | VV1691 | PBPRB0903 | PBPRA1859 | Putative NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Putative NAD-dependent protein deacetylase; Predicted by orpheus program; predicted by glimmer program; Belongs to the sirtuin family. Class III subfamily. | 0.901 |
| PLU2168 | VVA0411 | PBPRB0903 | PBPRB0912 | Putative NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Conserved hypothetical protein; Predicted by orpheus program; predicted by glimmer program; Belongs to the NadD family. | 0.903 |
| PLU3372 | C3138 | PBPRA0696 | PBPRA0694 | Putative heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several round [...] | Putative DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.670 |
| PLU3372 | PPNK | PBPRA0696 | PBPRA0695 | Putative heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several round [...] | Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.692 |
