node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GMK | PBPRA1638 | PBPRA0191 | PBPRA1638 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.937 |
GMK | PLU1241 | PBPRA0191 | PBPRA0836 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.960 |
GMK | S0103 | PBPRA0191 | PBPRB1716 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.928 |
GMK | S0421 | PBPRA0191 | PBPRA1016 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.960 |
GMK | SF0422 | PBPRA0191 | PBPRA1908 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative inosine-guanosine kinase; Predicted by orpheus program; predicted by glimmer program. | 0.905 |
GMK | T0175 | PBPRA0191 | PBPRA3180 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative hypoxanthine ribosyl transferase; Predicted by orpheus program; predicted by glimmer program; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.936 |
GMK | T0346 | PBPRA0191 | PBPRA0780 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.419 |
GMK | YPO3095 | PBPRA0191 | PBPRA1026 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative inosine-guanosine kinase; Predicted by orpheus program; predicted by glimmer program. | 0.905 |
GMK | guaA | PBPRA0191 | PBPRA0781 | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.963 |
PBPRA1638 | GMK | PBPRA1638 | PBPRA0191 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.937 |
PBPRA1638 | PLU1241 | PBPRA1638 | PBPRA0836 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.928 |
PBPRA1638 | S0103 | PBPRA1638 | PBPRB1716 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.915 |
PBPRA1638 | S0421 | PBPRA1638 | PBPRA1016 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.928 |
PBPRA1638 | S3149 | PBPRA1638 | PBPRA3148 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Hypothetical Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.906 |
PBPRA1638 | SF0422 | PBPRA1638 | PBPRA1908 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative inosine-guanosine kinase; Predicted by orpheus program; predicted by glimmer program. | 0.914 |
PBPRA1638 | T0175 | PBPRA1638 | PBPRA3180 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative hypoxanthine ribosyl transferase; Predicted by orpheus program; predicted by glimmer program; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.924 |
PBPRA1638 | T0346 | PBPRA1638 | PBPRA0780 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.937 |
PBPRA1638 | YPO3095 | PBPRA1638 | PBPRA1026 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative inosine-guanosine kinase; Predicted by orpheus program; predicted by glimmer program. | 0.914 |
PBPRA1638 | guaA | PBPRA1638 | PBPRA0781 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.941 |
PLU1241 | GMK | PBPRA0836 | PBPRA0191 | Putative xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.960 |