| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KDSB | LPXC | PBPRA2382 | PBPRA3210 | Putative 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Putative UDP-3-O-3-hydroxymyristoyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.880 |
| KDSB | NE2164 | PBPRA2382 | PBPRA2383 | Putative 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Conserved hypothetical protein; Predicted by orpheus program; predicted by glimmer program; Belongs to the UPF0434 family. | 0.925 |
| KDSB | PBPRA2386 | PBPRA2382 | PBPRA2386 | Putative 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Hypothetical Rec2-related protein; Predicted by orpheus program; predicted by glimmer program. | 0.676 |
| KDSB | STY0985 | PBPRA2382 | PBPRA2385 | Putative 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Putative transport ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.864 |
| KDSB | YCAH | PBPRA2382 | PBPRA2384 | Putative 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Putative tetraacyldisaccharide 4`-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.978 |
| KDSB | lpxB | PBPRA2382 | PBPRA2955 | Putative 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Putative lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.879 |
| LPXC | KDSB | PBPRA3210 | PBPRA2382 | Putative UDP-3-O-3-hydroxymyristoyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | Putative 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.880 |
| LPXC | STY0985 | PBPRA3210 | PBPRA2385 | Putative UDP-3-O-3-hydroxymyristoyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | Putative transport ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.512 |
| LPXC | YCAH | PBPRA3210 | PBPRA2384 | Putative UDP-3-O-3-hydroxymyristoyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | Putative tetraacyldisaccharide 4`-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.888 |
| LPXC | lpxB | PBPRA3210 | PBPRA2955 | Putative UDP-3-O-3-hydroxymyristoyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | Putative lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.890 |
| NE2164 | KDSB | PBPRA2383 | PBPRA2382 | Conserved hypothetical protein; Predicted by orpheus program; predicted by glimmer program; Belongs to the UPF0434 family. | Putative 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.925 |
| NE2164 | PBPRA2386 | PBPRA2383 | PBPRA2386 | Conserved hypothetical protein; Predicted by orpheus program; predicted by glimmer program; Belongs to the UPF0434 family. | Hypothetical Rec2-related protein; Predicted by orpheus program; predicted by glimmer program. | 0.676 |
| NE2164 | STY0985 | PBPRA2383 | PBPRA2385 | Conserved hypothetical protein; Predicted by orpheus program; predicted by glimmer program; Belongs to the UPF0434 family. | Putative transport ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.797 |
| NE2164 | YCAH | PBPRA2383 | PBPRA2384 | Conserved hypothetical protein; Predicted by orpheus program; predicted by glimmer program; Belongs to the UPF0434 family. | Putative tetraacyldisaccharide 4`-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.864 |
| PBPRA1667 | PBPRB0014 | PBPRA1667 | PBPRB0014 | Putative Beta-ketoacyl synthase; Predicted by orpheus program; predicted by glimmer program. | Hypothetical acyltransferase family protein; Predicted by orpheus program; predicted by glimmer program. | 0.997 |
| PBPRA1667 | STY0985 | PBPRA1667 | PBPRA2385 | Putative Beta-ketoacyl synthase; Predicted by orpheus program; predicted by glimmer program. | Putative transport ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.710 |
| PBPRA1667 | dnaK1 | PBPRA1667 | PBPRA0697 | Putative Beta-ketoacyl synthase; Predicted by orpheus program; predicted by glimmer program. | Putative DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.543 |
| PBPRA1667 | dnaK2 | PBPRA1667 | PBPRA1484 | Putative Beta-ketoacyl synthase; Predicted by orpheus program; predicted by glimmer program. | Putative chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.543 |
| PBPRA2386 | KDSB | PBPRA2386 | PBPRA2382 | Hypothetical Rec2-related protein; Predicted by orpheus program; predicted by glimmer program. | Putative 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.676 |
| PBPRA2386 | NE2164 | PBPRA2386 | PBPRA2383 | Hypothetical Rec2-related protein; Predicted by orpheus program; predicted by glimmer program. | Conserved hypothetical protein; Predicted by orpheus program; predicted by glimmer program; Belongs to the UPF0434 family. | 0.676 |