STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemAPutative glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (420 aa)    
Predicted Functional Partners:
HEML
Putative glutamate-1-semialdehyde 2,1-aminomutase; Predicted by orpheus program; predicted by glimmer program.
 
 0.989
HEMC
Putative porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.984
gltX
Putative glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
     
 0.923
S3879
Hypothetical protein; Predicted by orpheus program; predicted by glimmer program.
 
  
 0.914
PRFA
Putative peptide chain release factor A; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
  
 0.865
HEMB
Putative delta-aminolevulinic acid dehydratase; Predicted by orpheus program; predicted by glimmer program; Belongs to the ALAD family.
 
  
 0.855
HEMK
Putative HemK protein, Methylase of polypeptide chain release factors; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
     
 0.832
PP3999
Putative uroporphyrin-III C-methyltransferase; Predicted by orpheus program; predicted by glimmer program.
 
  
 0.782
T4028
Putative Uroporphyrinogen-III methylase; Predicted by orpheus program; predicted by glimmer program; Belongs to the precorrin methyltransferase family.
 
  
 0.780
S1301
Hypothetical protein; Predicted by orpheus program; predicted by glimmer program.
       0.775
Your Current Organism:
Photobacterium profundum
NCBI taxonomy Id: 298386
Other names: P. profundum SS9, Photobacterium SS9, Photobacterium profundum SS9, Photobacterium profundum str. SS9, Photobacterium profundum strain SS9, Photobacterium sp. (strain SS9), Photobacterium sp. SS9, deep-sea eubacterium SS9
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.