node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HD1188 | LPXA | PBPRA2957 | PBPRA2956 | 3R-hydroxymyristoyl-acyl-carrier-protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | Putative Acyl-UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.989 |
HD1188 | PBPRB0014 | PBPRA2957 | PBPRB0014 | 3R-hydroxymyristoyl-acyl-carrier-protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | Hypothetical acyltransferase family protein; Predicted by orpheus program; predicted by glimmer program. | 0.711 |
HD1188 | lpxB | PBPRA2957 | PBPRA2955 | 3R-hydroxymyristoyl-acyl-carrier-protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | Putative lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.911 |
HD1188 | rnhB | PBPRA2957 | PBPRA2954 | 3R-hydroxymyristoyl-acyl-carrier-protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | Putative ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.852 |
LPXA | HD1188 | PBPRA2956 | PBPRA2957 | Putative Acyl-UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3R-hydroxymyristoyl-acyl-carrier-protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.989 |
LPXA | lpxB | PBPRA2956 | PBPRA2955 | Putative Acyl-UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Putative lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.995 |
LPXA | rnhB | PBPRA2956 | PBPRA2954 | Putative Acyl-UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Putative ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.907 |
PBPRA1876 | PLU0942 | PBPRA1876 | PBPRA2918 | Hypothetical ribonuclease HI; Predicted by orpheus program; predicted by glimmer program. | Putative ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.922 |
PBPRA1876 | rnhB | PBPRA1876 | PBPRA2954 | Hypothetical ribonuclease HI; Predicted by orpheus program; predicted by glimmer program. | Putative ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.811 |
PBPRB0014 | HD1188 | PBPRB0014 | PBPRA2957 | Hypothetical acyltransferase family protein; Predicted by orpheus program; predicted by glimmer program. | 3R-hydroxymyristoyl-acyl-carrier-protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.711 |
PBPRB0014 | WS0479 | PBPRB0014 | PBPRB0250 | Hypothetical acyltransferase family protein; Predicted by orpheus program; predicted by glimmer program. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.920 |
PBPRB0014 | rnhB | PBPRB0014 | PBPRA2954 | Hypothetical acyltransferase family protein; Predicted by orpheus program; predicted by glimmer program. | Putative ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.897 |
PLU0002 | VV0679 | PBPRA0009 | PBPRA0581 | Putative DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...] | Putative thymidylate synthetase (thyA); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.907 |
PLU0002 | rnhB | PBPRA0009 | PBPRA2954 | Putative DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...] | Putative ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.918 |
PLU0942 | PBPRA1876 | PBPRA2918 | PBPRA1876 | Putative ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Hypothetical ribonuclease HI; Predicted by orpheus program; predicted by glimmer program. | 0.922 |
PLU0942 | rnhB | PBPRA2918 | PBPRA2954 | Putative ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Putative ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.811 |
SO1347 | rnhB | PBPRA3090 | PBPRA2954 | Putative signal peptidase I; Predicted by orpheus program; predicted by glimmer program; Belongs to the peptidase S26 family. | Putative ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.769 |
VV0679 | PLU0002 | PBPRA0581 | PBPRA0009 | Putative thymidylate synthetase (thyA); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Putative DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...] | 0.907 |
VV0679 | rnhB | PBPRA0581 | PBPRA2954 | Putative thymidylate synthetase (thyA); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Putative ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.888 |
WS0479 | PBPRB0014 | PBPRB0250 | PBPRB0014 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Hypothetical acyltransferase family protein; Predicted by orpheus program; predicted by glimmer program. | 0.920 |