node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C0532 | STY3484 | PBPRA0806 | PBPRA0393 | Putative geranyltranstransferase; Predicted by orpheus program; predicted by glimmer program; Belongs to the FPP/GGPP synthase family. | Putative octaprenyl-diphosphate synthase; Predicted by orpheus program; predicted by glimmer program; Belongs to the FPP/GGPP synthase family. | 0.924 |
C0532 | dxr | PBPRA0806 | PBPRA2962 | Putative geranyltranstransferase; Predicted by orpheus program; predicted by glimmer program; Belongs to the FPP/GGPP synthase family. | Putative 1-deoxy-D-xylulose 5-phosphatereductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.468 |
C0532 | uppS | PBPRA0806 | PBPRA2964 | Putative geranyltranstransferase; Predicted by orpheus program; predicted by glimmer program; Belongs to the FPP/GGPP synthase family. | Putative undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.966 |
HD1193 | S0169 | PBPRA2963 | PBPRA2961 | Putative phosphatidate cytidylyltransferase; Predicted by orpheus program; predicted by glimmer program; Belongs to the CDS family. | Putative membrane-associated Zn-dependent protease; Predicted by orpheus program; predicted by glimmer program. | 0.891 |
HD1193 | dxr | PBPRA2963 | PBPRA2962 | Putative phosphatidate cytidylyltransferase; Predicted by orpheus program; predicted by glimmer program; Belongs to the CDS family. | Putative 1-deoxy-D-xylulose 5-phosphatereductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.946 |
HD1193 | frr | PBPRA2963 | PBPRA2965 | Putative phosphatidate cytidylyltransferase; Predicted by orpheus program; predicted by glimmer program; Belongs to the CDS family. | Putative ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.690 |
HD1193 | uppS | PBPRA2963 | PBPRA2964 | Putative phosphatidate cytidylyltransferase; Predicted by orpheus program; predicted by glimmer program; Belongs to the CDS family. | Putative undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.956 |
HD1463 | T3205 | PBPRA0610 | PBPRA0611 | Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | Putative transcription pausing L factor; Participates in both transcription termination and antitermination. | 0.965 |
HD1463 | frr | PBPRA0610 | PBPRA2965 | Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | Putative ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.518 |
HD1463 | uppS | PBPRA0610 | PBPRA2964 | Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | Putative undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.874 |
PROS | S0169 | PBPRA2944 | PBPRA2961 | Putative prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and inv [...] | Putative membrane-associated Zn-dependent protease; Predicted by orpheus program; predicted by glimmer program. | 0.546 |
PROS | dxr | PBPRA2944 | PBPRA2962 | Putative prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and inv [...] | Putative 1-deoxy-D-xylulose 5-phosphatereductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.524 |
PROS | frr | PBPRA2944 | PBPRA2965 | Putative prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and inv [...] | Putative ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.519 |
PROS | uppS | PBPRA2944 | PBPRA2964 | Putative prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and inv [...] | Putative undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.878 |
S0169 | HD1193 | PBPRA2961 | PBPRA2963 | Putative membrane-associated Zn-dependent protease; Predicted by orpheus program; predicted by glimmer program. | Putative phosphatidate cytidylyltransferase; Predicted by orpheus program; predicted by glimmer program; Belongs to the CDS family. | 0.891 |
S0169 | PROS | PBPRA2961 | PBPRA2944 | Putative membrane-associated Zn-dependent protease; Predicted by orpheus program; predicted by glimmer program. | Putative prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and inv [...] | 0.546 |
S0169 | T3205 | PBPRA2961 | PBPRA0611 | Putative membrane-associated Zn-dependent protease; Predicted by orpheus program; predicted by glimmer program. | Putative transcription pausing L factor; Participates in both transcription termination and antitermination. | 0.498 |
S0169 | dxr | PBPRA2961 | PBPRA2962 | Putative membrane-associated Zn-dependent protease; Predicted by orpheus program; predicted by glimmer program. | Putative 1-deoxy-D-xylulose 5-phosphatereductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.913 |
S0169 | frr | PBPRA2961 | PBPRA2965 | Putative membrane-associated Zn-dependent protease; Predicted by orpheus program; predicted by glimmer program. | Putative ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.618 |
S0169 | uppS | PBPRA2961 | PBPRA2964 | Putative membrane-associated Zn-dependent protease; Predicted by orpheus program; predicted by glimmer program. | Putative undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.926 |