STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
STY2088Putative DNA damage-inducible gene in SOSregulon, dependent on cyclic AMP and H-NS; Predicted by orpheus program; predicted by glimmer program. (102 aa)    
Predicted Functional Partners:
PBPRA1578
Hypothetical SulA, SOS-response cell division inhibitor, blocks FtsZring formation; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
   
  
 0.849
lexA
Putative LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
   
  
 0.820
UMUD
Hypothetical protein; Predicted by orpheus program; predicted by glimmer program; Belongs to the peptidase S24 family.
   
  
 0.820
C3138
Putative DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.810
PSPTO168
Conserved hypothetical protein; Predicted by orpheus program; predicted by glimmer program.
 
     0.677
RECA
Putative RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
  
 0.595
PA3666
Putative 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
       0.585
STY2465
Conserved hypothetical protein; Predicted by orpheus program; predicted by glimmer program; Belongs to the UPF0352 family.
  
     0.578
STM2669
Putative chorismate mutase/prephenate dehydrogenase; Predicted by orpheus program; predicted by glimmer program.
  
     0.532
VVA1313
Conserved hypothetical protein; Predicted by orpheus program; predicted by glimmer program.
  
    0.507
Your Current Organism:
Photobacterium profundum
NCBI taxonomy Id: 298386
Other names: P. profundum SS9, Photobacterium SS9, Photobacterium profundum SS9, Photobacterium profundum str. SS9, Photobacterium profundum strain SS9, Photobacterium sp. (strain SS9), Photobacterium sp. SS9, deep-sea eubacterium SS9
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