STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
YPO0897Conserved hypothetical protein; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well. (88 aa)    
Predicted Functional Partners:
YPO1111
Putative succinate dehydrogenase, flavoprotein subunit; Predicted by orpheus program; predicted by glimmer program; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.923
S4577
Putative Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Predicted by orpheus program; predicted by glimmer program.
  
 0.906
SO0227
Putative ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
   0.800
PLU1372
Putative nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
   0.793
PBPRA3098
Hypothetical cell shape-determining protein; Predicted by orpheus program; predicted by glimmer program.
       0.784
YPO1110
Putative succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
 
     0.727
PBPRA0741
Hypothetical trypsin-like serine protease; Predicted by orpheus program; predicted by glimmer program.
    
   0.680
PBPRB0875
Hypothetical protein; Predicted by orpheus program; predicted by glimmer program.
    
   0.680
VV10447
Hypothetical trypsin-like serine protease; Predicted by orpheus program; predicted by glimmer program.
    
   0.680
Y3071
Putative succinate dehydrogenase; Predicted by orpheus program; predicted by glimmer program.
 
  
 0.660
Your Current Organism:
Photobacterium profundum
NCBI taxonomy Id: 298386
Other names: P. profundum SS9, Photobacterium SS9, Photobacterium profundum SS9, Photobacterium profundum str. SS9, Photobacterium profundum strain SS9, Photobacterium sp. (strain SS9), Photobacterium sp. SS9, deep-sea eubacterium SS9
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