node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ECS0533 | PBPRA1638 | PBPRA2836 | PBPRA1638 | Predicted by orpheus program; predicted by glimmer program; Belongs to the 5'-nucleotidase family. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.900 |
ECS0533 | PLU1241 | PBPRA2836 | PBPRA0836 | Predicted by orpheus program; predicted by glimmer program; Belongs to the 5'-nucleotidase family. | Putative xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.904 |
ECS0533 | S3149 | PBPRA2836 | PBPRA3148 | Predicted by orpheus program; predicted by glimmer program; Belongs to the 5'-nucleotidase family. | Hypothetical Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.900 |
ECS0533 | T0175 | PBPRA2836 | PBPRA3180 | Predicted by orpheus program; predicted by glimmer program; Belongs to the 5'-nucleotidase family. | Putative hypoxanthine ribosyl transferase; Predicted by orpheus program; predicted by glimmer program; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.900 |
ECS0533 | T0346 | PBPRA2836 | PBPRA0780 | Predicted by orpheus program; predicted by glimmer program; Belongs to the 5'-nucleotidase family. | Putative inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.915 |
ECS0533 | guaA | PBPRA2836 | PBPRA0781 | Predicted by orpheus program; predicted by glimmer program; Belongs to the 5'-nucleotidase family. | Putative GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.910 |
ECS0533 | surE | PBPRA2836 | PBPRA3074 | Predicted by orpheus program; predicted by glimmer program; Belongs to the 5'-nucleotidase family. | Putative acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.916 |
MURI | S3149 | PBPRA3462 | PBPRA3148 | Putative glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Hypothetical Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.900 |
PBPRA1638 | ECS0533 | PBPRA1638 | PBPRA2836 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Predicted by orpheus program; predicted by glimmer program; Belongs to the 5'-nucleotidase family. | 0.900 |
PBPRA1638 | PLU1241 | PBPRA1638 | PBPRA0836 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.928 |
PBPRA1638 | S3149 | PBPRA1638 | PBPRA3148 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Hypothetical Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.906 |
PBPRA1638 | T0175 | PBPRA1638 | PBPRA3180 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative hypoxanthine ribosyl transferase; Predicted by orpheus program; predicted by glimmer program; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.924 |
PBPRA1638 | T0346 | PBPRA1638 | PBPRA0780 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.937 |
PBPRA1638 | guaA | PBPRA1638 | PBPRA0781 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.941 |
PBPRA1638 | surE | PBPRA1638 | PBPRA3074 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
PLU1241 | ECS0533 | PBPRA0836 | PBPRA2836 | Putative xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Predicted by orpheus program; predicted by glimmer program; Belongs to the 5'-nucleotidase family. | 0.904 |
PLU1241 | PBPRA1638 | PBPRA0836 | PBPRA1638 | Putative xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.928 |
PLU1241 | S3149 | PBPRA0836 | PBPRA3148 | Putative xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Hypothetical Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.921 |
PLU1241 | T0175 | PBPRA0836 | PBPRA3180 | Putative xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Putative hypoxanthine ribosyl transferase; Predicted by orpheus program; predicted by glimmer program; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.928 |
PLU1241 | T0346 | PBPRA0836 | PBPRA0780 | Putative xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Putative inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.983 |