Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
S0117Putative aconitate hydratase 2; Predicted by orpheus program; predicted by glimmer program; Belongs to the aconitase/IPM isomerase family. (865 aa)    
Predicted Functional Partners:
T1682
Putative isocitrate dehydrogenase, specific forNADP+; Predicted by orpheus program; predicted by glimmer program.
  
 
 0.990
STY0773
Putative citrate synthase; Predicted by orpheus program; predicted by glimmer program; Belongs to the citrate synthase family.
  
 
 0.965
CBU0772
Putative methylcitrate synthase; Predicted by orpheus program; predicted by glimmer program; Belongs to the citrate synthase family.
  
 
 0.965
CBU0772-2
Putative methylcitrate synthase; Predicted by orpheus program; predicted by glimmer program; Belongs to the citrate synthase family.
  
 
 0.965
PLU1432
Putative succinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.935
T4112
Putative isocitrate lyase; Predicted by orpheus program; predicted by glimmer program.
   
 
 0.931
BA2349
Putative 2-methylcitrate dehydratase; Predicted by orpheus program; predicted by glimmer program.
     
 0.930
RS03568
Putative carboxyphosphonoenolpyruvate phosphonomutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
  
 
 0.927
T2140
Putative 2-oxoglutarate dehydrogenase, E1 component; Predicted by orpheus program; predicted by glimmer program.
   
  
 0.926
MDH
Putative malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
  
 0.924
Your Current Organism:
Photobacterium profundum
NCBI taxonomy Id: 298386
Other names: P. profundum SS9, Photobacterium SS9, Photobacterium profundum SS9, Photobacterium profundum str. SS9, Photobacterium profundum strain SS9, Photobacterium sp. (strain SS9), Photobacterium sp. SS9, deep-sea eubacterium SS9
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.