STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S4600Putative adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (432 aa)    
Predicted Functional Partners:
T0346
Putative inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
 
 0.993
SF4078
Putative osphoribosylaminoimidazolecarboxamideformyltransferase/IMP cyclohydrolase; Predicted by orpheus program; predicted by glimmer program.
  
 0.991
S0103
Putative GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
 
 
 0.991
T1688
Putative adenylosuccinate lyase; Predicted by orpheus program; predicted by glimmer program; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 0.990
guaA
Putative GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
  
 0.967
argG
Putative argininosuccinate synthase; Predicted by orpheus program; predicted by glimmer program; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.930
PYRB
Putative aspartate transcarbamylase catalytic subunit; Predicted by orpheus program; predicted by glimmer program; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
 
 0.928
YPO3095
Putative inosine-guanosine kinase; Predicted by orpheus program; predicted by glimmer program.
  
 0.924
SF0422
Putative inosine-guanosine kinase; Predicted by orpheus program; predicted by glimmer program.
  
 0.924
Y1198
Putative asparagine synthetase B, glutamine-hydrolyzing; Predicted by orpheus program; predicted by glimmer program.
  
 
 0.923
Your Current Organism:
Photobacterium profundum
NCBI taxonomy Id: 298386
Other names: P. profundum SS9, Photobacterium SS9, Photobacterium profundum SS9, Photobacterium profundum str. SS9, Photobacterium profundum strain SS9, Photobacterium sp. (strain SS9), Photobacterium sp. SS9, deep-sea eubacterium SS9
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.