STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACSPutative acetyl-CoA synthase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (649 aa)    
Predicted Functional Partners:
ECS2000
Putative pyruvate oxidoreductase; Predicted by orpheus program; predicted by glimmer program.
  
 
 0.965
SPYM3_13
Putative acetyl-CoA acetyltransferase; Predicted by orpheus program; predicted by glimmer program; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.938
STY0773
Putative citrate synthase; Predicted by orpheus program; predicted by glimmer program; Belongs to the citrate synthase family.
  
 0.933
CBU0772
Putative methylcitrate synthase; Predicted by orpheus program; predicted by glimmer program; Belongs to the citrate synthase family.
  
 0.933
S3511
Putative acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.933
CBU0772-2
Putative methylcitrate synthase; Predicted by orpheus program; predicted by glimmer program; Belongs to the citrate synthase family.
  
 0.933
Z3559
Putative phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.932
C4971
Putative malate synthase A; Predicted by orpheus program; predicted by glimmer program; Belongs to the malate synthase family.
   
 0.929
ACEB
Putative malate synthase A; Predicted by orpheus program; predicted by glimmer program.
   
 0.929
PA3925
Putative acyl-CoA thiolase; Predicted by orpheus program; predicted by glimmer program; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.928
Your Current Organism:
Photobacterium profundum
NCBI taxonomy Id: 298386
Other names: P. profundum SS9, Photobacterium SS9, Photobacterium profundum SS9, Photobacterium profundum str. SS9, Photobacterium profundum strain SS9, Photobacterium sp. (strain SS9), Photobacterium sp. SS9, deep-sea eubacterium SS9
Server load: low (28%) [HD]