| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ECS0498 | SO2179 | PBPRA0968 | PBPRB0335 | Putative exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.938 |
| ECS0498 | STY3080 | PBPRA0968 | PBPRA2333 | Putative exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Putative organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.998 |
| ECS0498 | T2876 | PBPRA0968 | PBPRA2982 | Putative exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.995 |
| ECS0498 | YPO3455 | PBPRA0968 | PBPRB0443 | Putative exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Putative anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.831 |
| ECS0498 | folE | PBPRA0968 | PBPRA2009 | Putative exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | GTP cyclohydrolase I; Predicted by orpheus program; predicted by glimmer program. | 0.536 |
| PBPRA0441 | SO2179 | PBPRA0441 | PBPRB0335 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.543 |
| PBPRA0441 | VV10016 | PBPRA0441 | PBPRA2630 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.713 |
| S0465 | SO2179 | PBPRA1098 | PBPRB0335 | Putative cysteinyl-tRNA synthetase; Predicted by orpheus program; predicted by glimmer program; Belongs to the class-I aminoacyl-tRNA synthetase family. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.562 |
| S0465 | VV12913 | PBPRA1098 | PBPRA1085 | Putative cysteinyl-tRNA synthetase; Predicted by orpheus program; predicted by glimmer program; Belongs to the class-I aminoacyl-tRNA synthetase family. | Putative phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; Predicted by orpheus program; predicted by glimmer program; In the C-terminal section; belongs to the PRA-PH family. | 0.567 |
| S0465 | cysS2 | PBPRA1098 | PBPRB1226 | Putative cysteinyl-tRNA synthetase; Predicted by orpheus program; predicted by glimmer program; Belongs to the class-I aminoacyl-tRNA synthetase family. | Hypothetical cysteinyl-tRNA synthetase (cysS); Predicted by orpheus program; predicted by glimmer program; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.917 |
| SO2179 | ECS0498 | PBPRB0335 | PBPRA0968 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.938 |
| SO2179 | PBPRA0441 | PBPRB0335 | PBPRA0441 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.543 |
| SO2179 | S0465 | PBPRB0335 | PBPRA1098 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative cysteinyl-tRNA synthetase; Predicted by orpheus program; predicted by glimmer program; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.562 |
| SO2179 | STY3080 | PBPRB0335 | PBPRA2333 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.880 |
| SO2179 | T2876 | PBPRB0335 | PBPRA2982 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.928 |
| SO2179 | VV10016 | PBPRB0335 | PBPRA2630 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.643 |
| SO2179 | VV12913 | PBPRB0335 | PBPRA1085 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; Predicted by orpheus program; predicted by glimmer program; In the C-terminal section; belongs to the PRA-PH family. | 0.609 |
| SO2179 | YPO3455 | PBPRB0335 | PBPRB0443 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.871 |
| SO2179 | cysS2 | PBPRB0335 | PBPRB1226 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Hypothetical cysteinyl-tRNA synthetase (cysS); Predicted by orpheus program; predicted by glimmer program; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.562 |
| SO2179 | folE | PBPRB0335 | PBPRA2009 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | GTP cyclohydrolase I; Predicted by orpheus program; predicted by glimmer program. | 0.714 |