STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
YPO1315Hypothetical hydrolase; Predicted by orpheus program; predicted by glimmer program. (234 aa)    
Predicted Functional Partners:
VV12913
Putative phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; Predicted by orpheus program; predicted by glimmer program; In the C-terminal section; belongs to the PRA-PH family.
  
  
 0.940
S2208
Putative imidazoleglycerol-phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.846
SF2085
Putative glutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.828
hisA
Putative phosphoribosylformimino-5-aminoimidazole carboxamideribonucleotide isomerase; Predicted by orpheus program; predicted by glimmer program.
  
  
 0.784
hisB
Putative imidazoleglycerol-phosphatedehydratase/histidinol- phosphatase; Predicted by orpheus program; predicted by glimmer program; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
  
  
 0.778
VV1351
Putative histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
  
 0.668
ECS2000
Putative pyruvate oxidoreductase; Predicted by orpheus program; predicted by glimmer program.
     
 0.614
hisC
Putative histidinol-phosphate aminotransferase; Predicted by orpheus program; predicted by glimmer program; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
 0.592
HISC
Putative histidinol phosphate aminotransferase; Predicted by orpheus program; predicted by glimmer program.
  
  
 0.592
ARGA
Putative N-acetylglutamate synthase; Predicted by orpheus program; predicted by glimmer program.
 
  
 0.572
Your Current Organism:
Photobacterium profundum
NCBI taxonomy Id: 298386
Other names: P. profundum SS9, Photobacterium SS9, Photobacterium profundum SS9, Photobacterium profundum str. SS9, Photobacterium profundum strain SS9, Photobacterium sp. (strain SS9), Photobacterium sp. SS9, deep-sea eubacterium SS9
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.