STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
XAC1542Putative fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (508 aa)    
Predicted Functional Partners:
MDH
Putative malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 0.990
YPO1111
Putative succinate dehydrogenase, flavoprotein subunit; Predicted by orpheus program; predicted by glimmer program; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.989
S4577
Putative Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Predicted by orpheus program; predicted by glimmer program.
 0.988
RS03529
Putative fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.982
T4394
Putative fumarate reductase, iron-sulfur protein; Predicted by orpheus program; predicted by glimmer program; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 0.970
STY0778
Putative succinate dehydrogenase, iron-sulfur protein; Predicted by orpheus program; predicted by glimmer program; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.966
STY0773
Putative citrate synthase; Predicted by orpheus program; predicted by glimmer program; Belongs to the citrate synthase family.
   
 0.962
CBU0772
Putative methylcitrate synthase; Predicted by orpheus program; predicted by glimmer program; Belongs to the citrate synthase family.
   
 0.962
CBU0772-2
Putative methylcitrate synthase; Predicted by orpheus program; predicted by glimmer program; Belongs to the citrate synthase family.
   
 0.962
Y3071
Putative succinate dehydrogenase; Predicted by orpheus program; predicted by glimmer program.
   
 
 0.961
Your Current Organism:
Photobacterium profundum
NCBI taxonomy Id: 298386
Other names: P. profundum SS9, Photobacterium SS9, Photobacterium profundum SS9, Photobacterium profundum str. SS9, Photobacterium profundum strain SS9, Photobacterium sp. (strain SS9), Photobacterium sp. SS9, deep-sea eubacterium SS9
Server load: low (20%) [HD]