STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C2630Putative phosphomethylpyrimidine kinase; Predicted by orpheus program; predicted by glimmer program. (276 aa)    
Predicted Functional Partners:
VC0062
Hypothetical thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 0.999
NCU07849
Putative transcriptional activator; Predicted by orpheus program; predicted by glimmer program.
 
 0.999
THIM
Putative hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
  
 0.995
THIC
Putative thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
 
 0.994
THIG
Putative thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.951
YPO3627
Hypothetical putative ABC transporter,ATP-binding; Predicted by orpheus program; predicted by glimmer program.
 
     0.851
AGR_L_30-3
Putative ABC transporter permease protein; Predicted by orpheus program; predicted by glimmer program.
 
     0.848
C0911
Putative molybdopterin biosynthesis MoeB protein; Predicted by orpheus program; predicted by glimmer program.
 
  
 0.761
BP0610
Putative molybdopterin biosynthesis MoeB protein; Predicted by orpheus program; predicted by glimmer program.
 
  
 0.759
AGR_L_30-2
Putative ABC transporter substrate-binding protein; Predicted by orpheus program; predicted by glimmer program.
 
     0.752
Your Current Organism:
Photobacterium profundum
NCBI taxonomy Id: 298386
Other names: P. profundum SS9, Photobacterium SS9, Photobacterium profundum SS9, Photobacterium profundum str. SS9, Photobacterium profundum strain SS9, Photobacterium sp. (strain SS9), Photobacterium sp. SS9, deep-sea eubacterium SS9
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