| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C4475 | CYAA | PBPRA0189 | PBPRA3526 | Putative guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Putative adenylate cyclase; Predicted by orpheus program; predicted by glimmer program; Belongs to the adenylyl cyclase class-1 family. | 0.901 |
| C4475 | PLU1372 | PBPRA0189 | PBPRA0759 | Putative guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Putative nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.923 |
| C4475 | PYKA | PBPRA0189 | PBPRA2431 | Putative guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Putative pyruvate kinase II; Predicted by orpheus program; predicted by glimmer program; Belongs to the pyruvate kinase family. | 0.914 |
| C4475 | S4514 | PBPRA0189 | PBPRB0442 | Putative guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Putative anaerobic ribonucleoside-triphosphate reductase; Predicted by orpheus program; predicted by glimmer program. | 0.911 |
| C4475 | STY3083 | PBPRA0189 | PBPRA3081 | Putative guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Putative MazG protein; Predicted by orpheus program; predicted by glimmer program. | 0.923 |
| C4475 | Y0811 | PBPRA0189 | PBPRA3082 | Putative guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Putative GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.918 |
| C4475 | Y1944 | PBPRA0189 | PBPRA0428 | Putative guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Putative pyruvate kinase I; Predicted by orpheus program; predicted by glimmer program; Belongs to the pyruvate kinase family. | 0.902 |
| C4475 | YPO1178 | PBPRA0189 | PBPRB0776 | Putative guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Putative adenylate cyclase CyaB; Predicted by orpheus program; predicted by glimmer program. | 0.900 |
| CYAA | C4475 | PBPRA3526 | PBPRA0189 | Putative adenylate cyclase; Predicted by orpheus program; predicted by glimmer program; Belongs to the adenylyl cyclase class-1 family. | Putative guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.901 |
| CYAA | PBPRA1658 | PBPRA3526 | PBPRA1658 | Putative adenylate cyclase; Predicted by orpheus program; predicted by glimmer program; Belongs to the adenylyl cyclase class-1 family. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.933 |
| CYAA | PLU1372 | PBPRA3526 | PBPRA0759 | Putative adenylate cyclase; Predicted by orpheus program; predicted by glimmer program; Belongs to the adenylyl cyclase class-1 family. | Putative nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
| CYAA | PLU3952 | PBPRA3526 | PBPRA0453 | Putative adenylate cyclase; Predicted by orpheus program; predicted by glimmer program; Belongs to the adenylyl cyclase class-1 family. | Putative cyclic AMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.964 |
| CYAA | PYKA | PBPRA3526 | PBPRA2431 | Putative adenylate cyclase; Predicted by orpheus program; predicted by glimmer program; Belongs to the adenylyl cyclase class-1 family. | Putative pyruvate kinase II; Predicted by orpheus program; predicted by glimmer program; Belongs to the pyruvate kinase family. | 0.901 |
| CYAA | S4514 | PBPRA3526 | PBPRB0442 | Putative adenylate cyclase; Predicted by orpheus program; predicted by glimmer program; Belongs to the adenylyl cyclase class-1 family. | Putative anaerobic ribonucleoside-triphosphate reductase; Predicted by orpheus program; predicted by glimmer program. | 0.914 |
| CYAA | STY3083 | PBPRA3526 | PBPRA3081 | Putative adenylate cyclase; Predicted by orpheus program; predicted by glimmer program; Belongs to the adenylyl cyclase class-1 family. | Putative MazG protein; Predicted by orpheus program; predicted by glimmer program. | 0.900 |
| CYAA | Y0811 | PBPRA3526 | PBPRA3082 | Putative adenylate cyclase; Predicted by orpheus program; predicted by glimmer program; Belongs to the adenylyl cyclase class-1 family. | Putative GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.901 |
| CYAA | Y1944 | PBPRA3526 | PBPRA0428 | Putative adenylate cyclase; Predicted by orpheus program; predicted by glimmer program; Belongs to the adenylyl cyclase class-1 family. | Putative pyruvate kinase I; Predicted by orpheus program; predicted by glimmer program; Belongs to the pyruvate kinase family. | 0.901 |
| CYAA | YPO1178 | PBPRA3526 | PBPRB0776 | Putative adenylate cyclase; Predicted by orpheus program; predicted by glimmer program; Belongs to the adenylyl cyclase class-1 family. | Putative adenylate cyclase CyaB; Predicted by orpheus program; predicted by glimmer program. | 0.976 |
| PBPRA1658 | CYAA | PBPRA1658 | PBPRA3526 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative adenylate cyclase; Predicted by orpheus program; predicted by glimmer program; Belongs to the adenylyl cyclase class-1 family. | 0.933 |
| PBPRA1658 | PLU3952 | PBPRA1658 | PBPRA0453 | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | Putative cyclic AMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.929 |