STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XAC1185Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. (169 aa)    
Predicted Functional Partners:
GMK
Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.923
PLU1372
Putative nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.918
PLU2764
Putative exopolyphosphatase; Predicted by orpheus program; predicted by glimmer program.
  
 
 0.910
SF3852
Putative exopolyphosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
  
 
 0.910
Y1944
Putative pyruvate kinase I; Predicted by orpheus program; predicted by glimmer program; Belongs to the pyruvate kinase family.
   
 
 0.902
PYKA
Putative pyruvate kinase II; Predicted by orpheus program; predicted by glimmer program; Belongs to the pyruvate kinase family.
   
 
 0.902
C4475
Putative guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.900
PA5497
Conserved hypothetical protein; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
     
  0.900
SF2316
Putative ribonucleoside-diphosphate reductase,alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
     
  0.900
NRDB
Putative ribonucleoside-diphosphate reductase,beta subunit; Predicted by orpheus program; predicted by glimmer program.
     
  0.900
Your Current Organism:
Photobacterium profundum
NCBI taxonomy Id: 298386
Other names: P. profundum SS9, Photobacterium SS9, Photobacterium profundum SS9, Photobacterium profundum str. SS9, Photobacterium profundum strain SS9, Photobacterium sp. (strain SS9), Photobacterium sp. SS9, deep-sea eubacterium SS9
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.