STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EF1354Putaive pyruvate dehydrogenase E1 component, beta subunit; Predicted by orpheus program; predicted by glimmer program. (327 aa)    
Predicted Functional Partners:
pdhA
Putative pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.999
RS04200
Putative dihydrolipoamide acetyltransferase; Predicted by orpheus program; predicted by glimmer program.
 
 0.999
STM0154
Putative pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component; Predicted by orpheus program; predicted by glimmer program.
 
 0.994
NMA1142
Putative pyridine nucleotide-disulfide oxidoreductase, class I; Predicted by orpheus program; predicted by glimmer program.
  
 0.991
SUCB
Putative 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.991
S0114
Putative pyruvate dehydrogenase E2 component dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.989
S1294
Putative phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.952
YPO1383
Putative formate acetyltransferase; Predicted by orpheus program; predicted by glimmer program.
   
 
 0.948
PM1235
Putative glutathione reductase; Predicted by orpheus program; predicted by glimmer program.
 
 0.939
PBPRA2113
Hypothetical protein; Predicted by orpheus program; predicted by glimmer program; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 0.938
Your Current Organism:
Photobacterium profundum
NCBI taxonomy Id: 298386
Other names: P. profundum SS9, Photobacterium SS9, Photobacterium profundum SS9, Photobacterium profundum str. SS9, Photobacterium profundum strain SS9, Photobacterium sp. (strain SS9), Photobacterium sp. SS9, deep-sea eubacterium SS9
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.