| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BC2803 | BIOD | PBPRB1138 | PBPRA2326 | Putative methyltransferase; Predicted by orpheus program; predicted by glimmer program. | Putative dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.895 |
| BC2803 | C4444 | PBPRB1138 | PBPRA1729 | Putative methyltransferase; Predicted by orpheus program; predicted by glimmer program. | Putative 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.803 |
| BC2803 | PBPRA1406 | PBPRB1138 | PBPRA1406 | Putative methyltransferase; Predicted by orpheus program; predicted by glimmer program. | Hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.512 |
| BC2803 | T2093 | PBPRB1138 | PBPRA2329 | Putative methyltransferase; Predicted by orpheus program; predicted by glimmer program. | Putative biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.919 |
| BC2803 | T3997 | PBPRB1138 | PBPRA0179 | Putative methyltransferase; Predicted by orpheus program; predicted by glimmer program. | Putative bioH protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.740 |
| BC2803 | VPA0711 | PBPRB1138 | PBPRB1749 | Putative methyltransferase; Predicted by orpheus program; predicted by glimmer program. | Putative aminotransferase, class II; Predicted by orpheus program; predicted by glimmer program. | 0.803 |
| BC2803 | VPA1299 | PBPRB1138 | PBPRB0449 | Putative methyltransferase; Predicted by orpheus program; predicted by glimmer program. | Hypothetical transcriptional regulator, TetR family; Predicted by orpheus program; predicted by glimmer program. | 0.585 |
| BC2803 | VV0135 | PBPRB1138 | PBPRA1786 | Putative methyltransferase; Predicted by orpheus program; predicted by glimmer program. | Hypothetical transcriptional regulator; Predicted by orpheus program; predicted by glimmer program. | 0.471 |
| BC2803 | Z0993 | PBPRB1138 | PBPRA2330 | Putative methyltransferase; Predicted by orpheus program; predicted by glimmer program. | Putative adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.558 |
| BC2803 | Z0995 | PBPRB1138 | PBPRA2328 | Putative methyltransferase; Predicted by orpheus program; predicted by glimmer program. | Putative 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.803 |
| BIOD | BC2803 | PBPRA2326 | PBPRB1138 | Putative dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Putative methyltransferase; Predicted by orpheus program; predicted by glimmer program. | 0.895 |
| BIOD | C4444 | PBPRA2326 | PBPRA1729 | Putative dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Putative 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.909 |
| BIOD | T2093 | PBPRA2326 | PBPRA2329 | Putative dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Putative biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.999 |
| BIOD | T3997 | PBPRA2326 | PBPRA0179 | Putative dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Putative bioH protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.738 |
| BIOD | VPA0711 | PBPRA2326 | PBPRB1749 | Putative dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Putative aminotransferase, class II; Predicted by orpheus program; predicted by glimmer program. | 0.930 |
| BIOD | Z0993 | PBPRA2326 | PBPRA2330 | Putative dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Putative adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.999 |
| BIOD | Z0995 | PBPRA2326 | PBPRA2328 | Putative dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Putative 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.993 |
| C4444 | BC2803 | PBPRA1729 | PBPRB1138 | Putative 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | Putative methyltransferase; Predicted by orpheus program; predicted by glimmer program. | 0.803 |
| C4444 | BIOD | PBPRA1729 | PBPRA2326 | Putative 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | Putative dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.909 |
| C4444 | T2093 | PBPRA1729 | PBPRA2329 | Putative 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | Putative biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.849 |