STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PI323Hypothetical ClpP family serine protease, possible phage related; Predicted by orpheus program; predicted by glimmer program; Belongs to the peptidase S14 family. (270 aa)    
Predicted Functional Partners:
CLPX
Putative ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
 
 0.982
PBPRB1288
Hypothetical phage portal protein; Predicted by orpheus program; predicted by glimmer program.
 
    0.953
PBPRB1286
Hypothetical gp36 major capsid-like protein; Predicted by orpheus program; predicted by glimmer program.
 
    0.907
C4793
Putative fatty oxidation complex, alpha subunit; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
   
  0.837
C2886
Putative fatty oxidation complex, alpha subunit; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
   
  0.837
CLPB
Putative ATPase with chaperone activity; Predicted by orpheus program; predicted by glimmer program; Belongs to the ClpA/ClpB family.
  
 
 0.823
YPO1368
Putative ATP-dependent Clp protease, ATP-binding subunit ClpA; Predicted by orpheus program; predicted by glimmer program; Belongs to the ClpA/ClpB family.
  
 
 0.823
PLU1270
Putative clpB, ATPases with chaperone activity; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belongs to the C [...]
  
 
 0.823
PBPRA1355
Hypothetical phage portal protein; Predicted by orpheus program; predicted by glimmer program.
 
    0.804
clpS
Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
   
 
 0.762
Your Current Organism:
Photobacterium profundum
NCBI taxonomy Id: 298386
Other names: P. profundum SS9, Photobacterium SS9, Photobacterium profundum SS9, Photobacterium profundum str. SS9, Photobacterium profundum strain SS9, Photobacterium sp. (strain SS9), Photobacterium sp. SS9, deep-sea eubacterium SS9
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