| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C5026 | DNAE | PBPRA3331 | PBPRA2953 | Putative Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Putative DNA polymerase III, alpha subunit; Predicted by orpheus program; predicted by glimmer program. | 0.798 |
| C5026 | ECS1190 | PBPRA3331 | PBPRA1310 | Putative Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Hypothetical bacteriophage replication protein P; Predicted by orpheus program; predicted by glimmer program. | 0.923 |
| C5026 | ECS1190-2 | PBPRA3331 | PBPRB1312 | Putative Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Hypothetical DNA helicase; Predicted by orpheus program; predicted by glimmer program. | 0.922 |
| C5026 | STY3389 | PBPRA3331 | PBPRA0431 | Putative Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Putative DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.961 |
| C5026 | TRMD | PBPRA3331 | PBPRA3039 | Putative Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Putative tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.537 |
| C5026 | VV0011 | PBPRA3331 | PBPRA0008 | Putative Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Putative DnaA chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.935 |
| C5026 | Y3619 | PBPRA3331 | PBPRA3209 | Putative Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Conserved hypothetical protein; Predicted by orpheus program; predicted by glimmer program. | 0.885 |
| C5026 | dnaX | PBPRA3331 | PBPRA1017 | Putative Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Hypothetical DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.694 |
| DNAE | C5026 | PBPRA2953 | PBPRA3331 | Putative DNA polymerase III, alpha subunit; Predicted by orpheus program; predicted by glimmer program. | Putative Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.798 |
| DNAE | ECS1190 | PBPRA2953 | PBPRA1310 | Putative DNA polymerase III, alpha subunit; Predicted by orpheus program; predicted by glimmer program. | Hypothetical bacteriophage replication protein P; Predicted by orpheus program; predicted by glimmer program. | 0.619 |
| DNAE | ECS1190-2 | PBPRA2953 | PBPRB1312 | Putative DNA polymerase III, alpha subunit; Predicted by orpheus program; predicted by glimmer program. | Hypothetical DNA helicase; Predicted by orpheus program; predicted by glimmer program. | 0.650 |
| DNAE | STY3389 | PBPRA2953 | PBPRA0431 | Putative DNA polymerase III, alpha subunit; Predicted by orpheus program; predicted by glimmer program. | Putative DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.758 |
| DNAE | TRMD | PBPRA2953 | PBPRA3039 | Putative DNA polymerase III, alpha subunit; Predicted by orpheus program; predicted by glimmer program. | Putative tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.500 |
| DNAE | VV0011 | PBPRA2953 | PBPRA0008 | Putative DNA polymerase III, alpha subunit; Predicted by orpheus program; predicted by glimmer program. | Putative DnaA chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.906 |
| DNAE | dnaX | PBPRA2953 | PBPRA1017 | Putative DNA polymerase III, alpha subunit; Predicted by orpheus program; predicted by glimmer program. | Hypothetical DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.991 |
| ECS1190 | C5026 | PBPRA1310 | PBPRA3331 | Hypothetical bacteriophage replication protein P; Predicted by orpheus program; predicted by glimmer program. | Putative Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.923 |
| ECS1190 | DNAE | PBPRA1310 | PBPRA2953 | Hypothetical bacteriophage replication protein P; Predicted by orpheus program; predicted by glimmer program. | Putative DNA polymerase III, alpha subunit; Predicted by orpheus program; predicted by glimmer program. | 0.619 |
| ECS1190 | ECS1190-2 | PBPRA1310 | PBPRB1312 | Hypothetical bacteriophage replication protein P; Predicted by orpheus program; predicted by glimmer program. | Hypothetical DNA helicase; Predicted by orpheus program; predicted by glimmer program. | 0.900 |
| ECS1190 | STY3389 | PBPRA1310 | PBPRA0431 | Hypothetical bacteriophage replication protein P; Predicted by orpheus program; predicted by glimmer program. | Putative DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.952 |
| ECS1190 | TRMD | PBPRA1310 | PBPRA3039 | Hypothetical bacteriophage replication protein P; Predicted by orpheus program; predicted by glimmer program. | Putative tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.613 |