STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
T1481Putative malate oxidoreductase; Predicted by orpheus program; predicted by glimmer program; Belongs to the malic enzymes family. (558 aa)    
Predicted Functional Partners:
ECS2000
Putative pyruvate oxidoreductase; Predicted by orpheus program; predicted by glimmer program.
    
 0.955
MDH
Putative malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 0.950
RS03529
Putative fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.944
XAC1542
Putative fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.940
Y1944
Putative pyruvate kinase I; Predicted by orpheus program; predicted by glimmer program; Belongs to the pyruvate kinase family.
  
 0.924
PYKA
Putative pyruvate kinase II; Predicted by orpheus program; predicted by glimmer program; Belongs to the pyruvate kinase family.
  
 0.924
DLD
Putative ferredoxin; Predicted by orpheus program; predicted by glimmer program.
  
 
 0.914
STM1349
Putative phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
   
 
 0.913
STM0152
Putative Pyruvate dehydrogenase complex,dehydrogenase component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.913
PLU2848
Putative D-lactate dehydrogenase, FAD protein, NADH independent; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.
 
 
 0.912
Your Current Organism:
Photobacterium profundum
NCBI taxonomy Id: 298386
Other names: P. profundum SS9, Photobacterium SS9, Photobacterium profundum SS9, Photobacterium profundum str. SS9, Photobacterium profundum strain SS9, Photobacterium sp. (strain SS9), Photobacterium sp. SS9, deep-sea eubacterium SS9
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