STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
grdA1Putative selenoprotein A of glycine-reductase; In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination (By similarity). (107 aa)    
Predicted Functional Partners:
PLSX2
Hypothetical Fatty acid/phospholipid biosynthesis enzyme; Predicted by orpheus program; predicted by glimmer program.
 
   
 0.897
FABH4
Hypothetical glycine reductase protein C; Predicted by orpheus program; predicted by glimmer program.
 
   
 0.895
GRDB
Hypothetical glycine reductase complex selenoprotein B; Predicted by orpheus program; predicted by glimmer program.
 
   
 0.865
GRDE
Hypothetical glycine reductase proprotein GrdE; Predicted by orpheus program; predicted by glimmer program.
 
   
 0.861
GRDX
Hypothetical GrdX protein; Predicted by orpheus program; predicted by glimmer program.
 
   
 0.801
TRXA-2
Hypothetical thioredoxin; Predicted by orpheus program; predicted by glimmer program; Belongs to the thioredoxin family.
 
   
 0.751
SPS0115
Hypothetical regulatory protein PfoR; Predicted by orpheus program; predicted by glimmer program.
  
     0.710
PBPRB1551
Hypothetical thioredoxin reductase; Predicted by orpheus program; predicted by glimmer program.
 
   
 0.703
grdA2
Putative glycine reductase complex selenoprotein A; In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination (By similarity).
 
  
 
0.653
EF0617
Hypothetical integral membrane protein; Predicted by orpheus program; predicted by glimmer program.
  
     0.579
Your Current Organism:
Photobacterium profundum
NCBI taxonomy Id: 298386
Other names: P. profundum SS9, Photobacterium SS9, Photobacterium profundum SS9, Photobacterium profundum str. SS9, Photobacterium profundum strain SS9, Photobacterium sp. (strain SS9), Photobacterium sp. SS9, deep-sea eubacterium SS9
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