STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ECS0359Putative transcriptional regulator; Repressor involved in choline regulation of the bet genes. (192 aa)    
Predicted Functional Partners:
VPA1112
Putative choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
 
  
 0.949
Z0399
Putative betaine aldehyde dehydrogenase; Predicted by orpheus program; predicted by glimmer program; Belongs to the aldehyde dehydrogenase family.
  
 0.939
PEGA
Hypothetical alcohol dehydrogenase; Predicted by orpheus program; predicted by glimmer program.
 
  
 0.783
AGR_C_41
Putative glycine betaine-binding ABC transporter; Predicted by orpheus program; predicted by glimmer program.
 
     0.758
BETT
Putative transporter, BCCT family (BetT, Choline-glycine betaine transporter); Predicted by orpheus program; predicted by glimmer program; Belongs to the BCCT transporter (TC 2.A.15) family.
  
  
 0.732
BETT-2
Putative transporter, BCCT family; Predicted by orpheus program; predicted by glimmer program; Belongs to the BCCT transporter (TC 2.A.15) family.
  
  
 0.732
ALDA
Putative aldehyde dehydrogenase; Predicted by orpheus program; predicted by glimmer program; Belongs to the aldehyde dehydrogenase family.
 
  
 0.576
PA0265
Putative succinate-semialdehyde dehydrogenase; Predicted by orpheus program; predicted by glimmer program; Belongs to the aldehyde dehydrogenase family.
 
  
 0.568
CLPB
Putative ATPase with chaperone activity; Predicted by orpheus program; predicted by glimmer program; Belongs to the ClpA/ClpB family.
      
 0.522
PLU1270
Putative clpB, ATPases with chaperone activity; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belongs to the C [...]
      
 0.522
Your Current Organism:
Photobacterium profundum
NCBI taxonomy Id: 298386
Other names: P. profundum SS9, Photobacterium SS9, Photobacterium profundum SS9, Photobacterium profundum str. SS9, Photobacterium profundum strain SS9, Photobacterium sp. (strain SS9), Photobacterium sp. SS9, deep-sea eubacterium SS9
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