STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1V6RG46Pyruvate carboxyltransferase domain-containing protein. (359 aa)    
Predicted Functional Partners:
A0A1V6SAJ1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
     
 0.935
A0A1V6RJS5
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 
 0.933
A0A1V6S5G9
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 
 0.933
A0A1V6RZ87
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.919
A0A1V6RWC6
Uncharacterized protein.
  
 
 0.912
A0A1V6S231
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.912
A0A1V6S5B3
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.912
A0A1V6S8F7
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.912
A0A1V6RHC2
Lipoyl-binding domain-containing protein.
     
 0.900
A0A1V6SE74
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.899
Your Current Organism:
Penicillium vulpinum
NCBI taxonomy Id: 29845
Other names: P. vulpinum, Penicillium claviforme
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