STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
ABW10440.1
TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes; Transketolase central region; KEGG: fal:FRAAL5981 2-oxoglutarate dehydrogenase, E1 component (SucA).
 
 
 0.998
ABW10730.1
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: fal:FRAAL5655 succinate dehydrogenase iron-sulfur protein.
 
 0.987
ABW10731.1
KEGG: fal:FRAAL5654 succinate dehydrogenase flavoprotein subunit A; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase.
 
 0.982
ABW11217.1
TIGRFAM: 2-oxoglutarate dehydrogenase E2 component; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: fal:FRAAL5152 dihydrolipoamide succinyltransferase, component of 2-oxoglutarate dehydrogenase complex (E2).
 
 0.974
ABW16546.1
KEGG: fal:FRAAL0111 citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
 
 
 0.966
ABW15421.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: fal:FRAAL1051 putative oxidoreductase,alpha subunit.
  
 
 0.962
ABW16201.1
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: fal:FRAAL6799 ferredoxin oxidoreductase alpha subunit.
  
 
 0.962
ABW16548.1
PFAM: Citrate synthase; KEGG: fal:FRAAL0109 citrate synthase 2; Belongs to the citrate synthase family.
  
 
 0.952
ABW13693.1
PFAM: cobalamin B12-binding domain protein; KEGG: mjl:Mjls_3811 cobalamin B12-binding domain protein.
  
 
 0.935
Your Current Organism:
Frankia sp. EAN1pec
NCBI taxonomy Id: 298653
Other names: F. sp. EAN1pec
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.