STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
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[Homology]
Score
mqnCRadical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (384 aa)    
Predicted Functional Partners:
mqnD
Protein of unknown function DUF178; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.
 
  
 0.987
mqnB
Futalosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
  
 0.984
ADP82918.1
Protein serine/threonine phosphatase; KEGG: fal:FRAAL4851 putative regulatory protein; PFAM: Stage II sporulation protein E; SMART: protein phosphatase 2C domain protein.
  
 
 0.949
mqnA
Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
   
 0.886
ADP84278.1
KEGG: fal:FRAAL1007 prenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; Belongs to the UbiA prenyltransferase family.
 
   
 0.816
menG
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
     
 0.813
ADP81139.1
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation protein E; PAS fold domain protein; response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: kfl:Kfla_4457 multi-sensor signal transduction histidine kinase; SMART: response regulator receiver; protein phosphatase 2C domain protein; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein.
  
 
 0.779
ADP84279.1
UbiD family decarboxylase; KEGG: fal:FRAAL1006 3-polyprenyl-4-hydroxybenzoate decarboxylase; TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; Belongs to the UbiD family.
 
   
 0.779
thiG
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 
 0.769
ADP84277.1
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; KEGG: fal:FRAAL1008 putative aromatic acid decarboxylase; TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein.
 
   
 0.765
Your Current Organism:
Frankia inefficax
NCBI taxonomy Id: 298654
Other names: CECT 9037, DSM 45817, F. inefficax, Frankia inefficax Nouioui et al. 2017, Frankia sp. EuI1c, strain EuI1c
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