| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DA2_0130 | pyrR | DA2_0130 | DA2_0114 | Putative lysine decarboxylase family protein; Belongs to the LOG family. | Bifunctional protein pyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.478 |
| DA2_0130 | tadA | DA2_0130 | DA2_0129 | Putative lysine decarboxylase family protein; Belongs to the LOG family. | Cytidine and deoxycytidylate deaminase zinc-binding region family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.748 |
| DA2_0130 | upp | DA2_0130 | DA2_1021 | Putative lysine decarboxylase family protein; Belongs to the LOG family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.476 |
| DA2_2074 | birA | DA2_2074 | DA2_1126 | glyoxalase/Bleomycin resistance /Dioxygenase superfamily protein. | biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.731 |
| DA2_2074 | tadA | DA2_2074 | DA2_0129 | glyoxalase/Bleomycin resistance /Dioxygenase superfamily protein. | Cytidine and deoxycytidylate deaminase zinc-binding region family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.750 |
| DA2_3403 | tadA | DA2_3403 | DA2_0129 | Tetrapyrrole (Corrin/Porphyrin) Methylases family protein. | Cytidine and deoxycytidylate deaminase zinc-binding region family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.698 |
| birA | DA2_2074 | DA2_1126 | DA2_2074 | biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | glyoxalase/Bleomycin resistance /Dioxygenase superfamily protein. | 0.731 |
| birA | guaA | DA2_1126 | DA2_3686 | biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.652 |
| birA | pyrR | DA2_1126 | DA2_0114 | biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Bifunctional protein pyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.485 |
| birA | ribBA | DA2_1126 | DA2_3654 | biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.589 |
| birA | tadA | DA2_1126 | DA2_0129 | biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Cytidine and deoxycytidylate deaminase zinc-binding region family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.898 |
| guaA | birA | DA2_3686 | DA2_1126 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.652 |
| guaA | purA | DA2_3686 | DA2_2223 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.957 |
| guaA | pyrR | DA2_3686 | DA2_0114 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Bifunctional protein pyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.538 |
| guaA | ribBA | DA2_3686 | DA2_3654 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.749 |
| guaA | tadA | DA2_3686 | DA2_0129 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Cytidine and deoxycytidylate deaminase zinc-binding region family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.647 |
| guaA | tilS | DA2_3686 | DA2_0320 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.865 |
| guaA | upp | DA2_3686 | DA2_1021 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.843 |
| purA | guaA | DA2_2223 | DA2_3686 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.957 |
| purA | ribBA | DA2_2223 | DA2_3654 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.517 |