DA2_0636 protein (Desulfovibrio sp. A2) - STRING interaction network

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Score

DA2_0636

dnaJ domain protein. (316 aa)

Predicted Functional Partners:

dnaK

0.997

grpE

0.980

groL

0.973

htpG

0.969

clpB

0.958

DA2_0635

0.949

clpA

0.927

cyp18

0.873

rpsG

0.872

ndk

0.871

Your Current Organism:

Desulfovibrio sp. A2

NCBI taxonomy Id: 298701
Other names: D. sp. A2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DA2_0635	DA2_0636	DA2_0635	DA2_0636	Hypothetical protein.	dnaJ domain protein.	0.949
DA2_0635	clpA	DA2_0635	DA2_0510	Hypothetical protein.	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	0.585
DA2_0635	clpB	DA2_0635	DA2_0634	Hypothetical protein.	ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.	0.816
DA2_0636	DA2_0635	DA2_0636	DA2_0635	dnaJ domain protein.	Hypothetical protein.	0.949
DA2_0636	clpA	DA2_0636	DA2_0510	dnaJ domain protein.	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	0.927
DA2_0636	clpB	DA2_0636	DA2_0634	dnaJ domain protein.	ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.	0.958
DA2_0636	cyp18	DA2_0636	DA2_0633	dnaJ domain protein.	Peptidyl-prolyl cis-trans isomerase cyp18; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.873
DA2_0636	dnaK	DA2_0636	DA2_3347	dnaJ domain protein.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.997
DA2_0636	groL	DA2_0636	DA2_3616	dnaJ domain protein.	Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family.	0.973
DA2_0636	grpE	DA2_0636	DA2_1365	dnaJ domain protein.	grpE family protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...]	0.980
DA2_0636	htpG	DA2_0636	DA2_1265	dnaJ domain protein.	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein; Molecular chaperone. Has ATPase activity.	0.969
DA2_0636	ndk	DA2_0636	DA2_3723	dnaJ domain protein.	Nucleoside diphosphate kinase family protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.871
DA2_0636	rpsG	DA2_0636	DA2_0024	dnaJ domain protein.	Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.	0.872
clpA	DA2_0635	DA2_0510	DA2_0635	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	Hypothetical protein.	0.585
clpA	DA2_0636	DA2_0510	DA2_0636	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	dnaJ domain protein.	0.927
clpA	dnaK	DA2_0510	DA2_3347	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.978
clpA	groL	DA2_0510	DA2_3616	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family.	0.730
clpA	grpE	DA2_0510	DA2_1365	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	grpE family protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...]	0.880
clpA	htpG	DA2_0510	DA2_1265	ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein; Molecular chaperone. Has ATPase activity.	0.937
clpB	DA2_0635	DA2_0634	DA2_0635	ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.	Hypothetical protein.	0.816