STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DA2_19813-dehydroquinate synthase. (323 aa)    
Predicted Functional Partners:
DA2_1980
Chorismate mutase type II family protein.
 
  
 0.986
griI
2-amino-4,5-dihydroxy-6-one-heptanoic acid-7-phosphate synthase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
 
 
 0.983
DA2_2257
Shikimate 5-dehydrogenase; Belongs to the shikimate dehydrogenase family.
 
  
 0.779
DA2_1982
Hypothetical protein.
       0.773
aroQ
Dehydroquinase class II family protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
     
 0.642
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
   
 0.617
DA2_1978
Prephenate dehydrogenase family protein.
 
     0.579
thrC
Threonine synthase.
  
  
 0.558
DA2_2819
Aminotransferase class IV family protein.
  
   
 0.513
DA2_1884
Tungsten formylmethanofuran dehydrogenase subunit E.
  
     0.508
Your Current Organism:
Desulfovibrio sp. A2
NCBI taxonomy Id: 298701
Other names: D. sp. A2
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